PlainPill

What people actually say

1,746 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
GlycineMostly positive
“2 grams with 200mg magnesium before bed gives me crazy good sleep. Crazy vivid dreams.”
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GlycineMostly positive
“Taking isolated glycine several days in a row makes me super groggy throughout the day. It puts me to sleep almost like a sedative.”
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GlycineMostly positive
“I take a lot of glycine...I take a couple of teaspoons of the powder every night and it helps me sleep without any sort of payback.”
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GlycineMostly positive
“I tried using glycine as a sleep aid for a while and it did the opposite. Turns out it's stimulating for some people and sedating for others.”
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5-HTPMixed
“I just one day randomly decided to take 5-HTP an hour after finishing my workout, and I felt WIRED 15 minutes after taking it, and that lasted for 5–6 hours.”
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5-HTPMixed
“I took 50mg of 5HTP and I went back to normal for a few days and was happier than ever, then I had a brutal hangover and later that day the same post-CBT feeling came back.”
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5-HTPMixed
“My mood was pretty well improved, felt happy and pretty 'sated.' Overall pleasant.”
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5-HTPMixed
“At night, 5htp has a wonderful effect on me. I sleep, and wake up feeling refreshed.”
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COQ10Mostly positive
“I rely on 200mg of Qunol Co-enzyme Q10 to take with my 40mg of Crestor to prevent statin side effects. Works wonderfully.”
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COQ10Mostly positive
“even the nootropics that some communities swear by did nothing for me (some that come to mind - racetams, tyrosine/NALT, NAC, methylated B vitamins...”
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COQ10Mostly positive
“I combined this with NootropicsDepot's Shilajit. Insane energy from this. Such clean mental energy and zero fatigue.”
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COQ10Mostly positive
“250mg Ubiquinol, 2tsp cod liver oil, and 5g creatine daily... Within about two weeks, I noticed my memory improving.”
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SemaxMostly positive
“The effects have been incredible. It feels like my background distractibility has just vanished. I can lock in and focus even when my phone and other distractions are right next to me.”
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SemaxMostly positive
“I think Semax actually made my brainfog much worse, or the combo of that and PE-22-28.”
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SemaxMostly positive
“Ran a cycle of semax for cognition, no changes noted but I feel this one is a long term process.”
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SemaxMostly positive
“This shit is the shit!! This is what I wish weed and alcohol felt like! I was chill, listened to music, got work done, didn't want to procrastinate. My ahedonia was gone. I hope this shit isn't dangerous because it is awesome.”
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Vitamin B12Mostly positive
“I supplemented with sublingual b12 and iron and daily electrolytes and I'm feeling much better.”
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Vitamin B12Mostly positive
“I tried so many things for depression like saffron rhodiola tyrosine omega 3 methylfolate B12 taurine theanine NAC inositol b complex magnesium nothing helps it.”
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Vitamin B12Mostly positive
“1. If I take early in the morning, it helps with circadian rhythm. 2. If I take more late, it helps with energy.”
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Vitamin B12Mostly positive
“Later lab tests uncovered both, and subsequent supplementation fixed a good deal of issues I had in terms of energy and sleep.”
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AniracetamMostly positive
“Aniracetam: Anecdotally I could feel instantaneous mental improvement within 2-3 days... The most significant improvement was attention... organization, and confidence.”
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AniracetamMostly positive
“This is the first time i've ever taken something that truly has improved my cognitive capacity. My mind has never been so clear.”
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AniracetamMostly positive
“I just feel more aware of everything. The strongest change is that the music I'm listening to sounds much better.”
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AniracetamMostly positive
“Overall I would say I improved 60% of my ADHD. Especially while Aniracetam is active in my system.”
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“I have a stack of supplements that I take specifically for recovery from the adderall and vyvanse that I researched thoroughly, and see huge positive results from.”
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“I took a friend's multivitamin the other day and noticed it really helped with both my mood and sleepiness.”
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“I first tried supplementation with Omega-3s, Curcumin phytosome, glutamine, multivitamins consistently, which I definitely think helped inflammation, but the problem persisted.”
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“more simple supplements like omega 3, multivitamins, creatine (for working out) and choline. None have helped with my mental consistency as of yet.”
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“Nicotine gum/pouches have been helpful for me especially when I am trying to focus at work.”
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“For me it's like a less anxiety inducing caffeine, with a stronger focus enhancement...For me, nicotine is better than most nootropics. And is only small step down from adderall.”
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“I craved it, but it also gave me dizziness, anxiety, and nausea at times which imo outweighs the cognitive enhancement.”
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“I had a lot more motivation, focus, and was a lot more calm.”
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MeditationMostly positive
“And my sleep? No more nightmares. I began sleeping soundly. I feel more rested from sleep than I have in decades.”
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MeditationMostly positive
“I've done years of CBT, mediation, psychotherapy, exercise, sunlight exposure, probiotics ... and they helped a lot with other stuff but not the anxiety.”
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MeditationMostly positive
“After ~10-15 minutes of meditation, it resets my brain like a computer and puts me in a new state of mind. It stops the racing thoughts--the feeling of my mind moving a mile a minute.”
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MeditationMostly positive
“After a night of sleep deprivation induced anti-depressant relief, I became insanely mindful and started dutifully watching and observing my thoughts...I've experienced and become more familiar with my thoughts, and realized that they're just sensations, just mental constructs, not 'me'.”
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GHK-CuMostly positive
“Love it. 44 F. Totally helped even out my skin tone (Irish red cheeks), reduced wrinkles on my forehead and neck, thickened my hair which had been thinning, and grew my eye lashes.”
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GHK-CuMostly positive
“My under-eye hollowness has not disappeared completely, but it has somewhat improved.”
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GHK-CuMostly positive
“The changes in my hair have been great, the growth rate has accelerated, the texture has improved, and there’s a noticeable shine that wasn’t there before.”
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GHK-CuMostly positive
“I (60F) inject my test subject 4mg/day. Started at 2mg in January and have seen dramatic changes in overall skin density and texture. Ive lost 96 lbs in 9 months with no loose skin or hair loss.”
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