PlainPill

What people actually say

1,817 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
Zinc PicolinateMostly positive
“Mine stopped a few days after I added zinc picolate. I take them at different times of the day.”
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Zinc PicolinateMostly positive
“Zinc picolinate - I’m zinc deficient and a lot of individuals with adhd have zinc deficiencies ... This helps with attention as well as immunity.”
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Grape Seed ExtractNot enough data
“anything which helps increase nitric oxide production like grape seed extract should in theory help. I haven’t used Vyvanse in many years but It’s worked for me more recently when using DMAA.”
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Grape Seed ExtractNot enough data
“I tried these on their own and they did not give the same effect, I don't think they ever helped on their own”
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Grape Seed ExtractNot enough data
“vitamin C and grapeseed extract. It's my alternative to medication as I used to be prescribed with ritalin. I can tell you from firsthand experience it worked just as well.”
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Grape Seed ExtractNot enough data
“For GSE, I felt a bit better (probably since I may or may not have shitty blood flow and GSE tends to help that most) but my gyno did not appear to be altered at all”
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CognanceMostly positive
“i swear to god cognance (i stack with saffron) helped me cope with my anxiety and ocd in a way no prescription med ever has.”
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CognanceMostly positive
“I've been taking it for about two weeks now with no noticeable results... but my experience has been the opposite. It has consistently for the past 3 weeks had a significant effect on my stress, anxiety and wellbeing.”
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CognanceMostly positive
“so far cognance has really helped with anxiety significantly... The past 3 nights I have only woken up once or twice.”
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CognanceMostly positive
“I use cognance and it seems to have helped my focus and anxiety.”
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“With taking the oil my pain reduced within 30 minutes to the point where I have not found it necessary to take any painkillers yet.”
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“When I started cooking with it I noticed an immediate increase in alertness and so on.”
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“I personally never noticed any effect from 1-2 tbsp of coconut oil.”
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“I also took coconut oil which has been said to help combat viruses and candida. Although I did feel better someone a lot of my symptoms still remained.”
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L-DopaMixed
“I find 4-hydroxyphenylalanine and L-γ-glutamylethylamide make a huge difference in keeping myself on an even keel..”
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L-DopaMixed
“L-Dopa is making me a bit anxious but sure helps me with depression and focus.”
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L-DopaMixed
“I have been taking L-Dopa and it has been working for me. My moods have been consistent and my anxiety have been almost non-existent.”
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L-DopaMixed
“I've taken both L-Dopa and 5-HTP before and they didn't do shit.”
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SarcosineMostly positive
“sarcosine + NAC nailed it. I literally cannot tell the difference. I feel so amazing.”
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SarcosineMostly positive
“long courses of Sarcosine (daily for a month+ at a time) helped tremendously and permanently, however when I tried it again more recently it triggered anxiety and overthinking.”
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SarcosineMostly positive
“GlyT1 Inhibitors: Sarcosine and (lesser extent) dimethylglycine cause glycine reuptake inhibition, proven quite effective for anxiety ... Helps me a lot.”
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SarcosineMostly positive
“2000mg sarcosine helps with the emotional blunting often seen in schizophrenia, and it aids cognitive performance through enhanced NMDA signaling. I have taken both for a few weeks and they have helped me tremendously.”
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Resistance TrainingMostly positive
“more weight training. I was pumping iron, but not often enough so I lost more muscle mass than what I needed to.”
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Resistance TrainingMostly positive
“I find resistance training especially effective. Quads, glutei, calves, triceps, biceps, shoulders, abs - get them all reasonable sore, and you crash like a baby.”
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Resistance TrainingMostly positive
“I made incredible strides and even worked through the right shoulder issue that had been hampering me for years.”
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Resistance TrainingMostly positive
“my hack to get it up without pharmaceuticals and have increased libido. Is doing lots of squats with weights”
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DihexaMostly positive
“The effects have been promising, because I found myself not only better in actual routine work, but also studying and learning, which was really hard to me before. It felt like combining mental clarity with neural plasticity.”
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DihexaMostly positive
“I've taken it three times, all orally. It's easily the most profound substance i've tried yet...Better memory and general retention, greater plasticity...improved physical performance”
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DihexaMostly positive
“fish oil psilocybin dihexa and fast for at least 24 hrs once per week... these are the things i feel were absolutely critical in my recovery.”
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DihexaMostly positive
“some peptides like dihexa, Cerebrolysin, selank, semax, and Retatrutide also helped my recovery”
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“I really got better from anxiety ... on effexor. My personal miracle drug does not work for everyone.”
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“I tried Venlafaxine and my ADHD improved significantly. However, it also had a certain amount of excitotoxicity, and I couldn't sleep at night.”
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“I started Venlafaxine three months ago when I got depressed again...and it got me out of bed, but NAC was the game changer for me.”
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“I found that Venlafaxine was good once it down regulated my norephineprine. Before I was constantly full of somatic anxiety but now it’s definitely improved.”
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SSRIMostly negative
“then i came to SSRI , it helped a little bit then.”
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SSRIMostly negative
“I only took them for those 25 days and quit because it made me feel 100% numb with zero emotions or pleasure.”
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SSRIMostly negative
“Started doing some therapy and an SSRI, and saw huge improvement in all my symptoms.”
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SSRIMostly negative
“I decided to try an SSRI one day and now my life has completely changed. Anxiety is gone, obsessive behavior/rituals are gone, agoraphobia is gone.”
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TribugenMostly positive
“I m getting great energy and insane libido EVERYDAY. I m 44.”
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TribugenMostly positive
“Taking 4 capsules in a day is where I started to feel really good, but just without the energy difference.”
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