What people actually say
1,588 first-hand quotes, shortened but never edited — each links to the original discussion.
AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
PramiracetamMixed
“I was very anxious and listless for a while and the substances that helped me the most were Pramiracetam + alpha GPC.”Source discussion ↗
PramiracetamMixed
“have been using pram for a few days and wondering if I should switch to noopept. In terms of effect, felt a wee bit more motivated, def had headaches for a short while.”Source discussion ↗
PramiracetamMixed
“By far the most potent nootropic I have tried. The biggest aspect that I have noticed is sense of well being and reduced anxiety. And one of the weirdest effects is I do not crave stimulants anymore.”Source discussion ↗
PramiracetamMixed
“Pramiracetam has always reliably worked for me. I find my recall is improved...but it made me too focused and had a blunting effect on my emotions.”Source discussion ↗
PhosphatidylserineMostly positive
“A supplement I have never seen on here that works great for me is Phosphatidylserine. Somehow awesome.”Source discussion ↗
PhosphatidylserineMostly positive
“I have been taking this...and I have had great results...From my research, I found phosphatidylserine to be of little to no benefit on cognitive function.”Source discussion ↗
PhosphatidylserineMostly positive
“Phosphatidylserine (8/10): ... it made a pretty big impact as far as stress reduction for me. I felt less physical anxiety in social situations...”Source discussion ↗
PhosphatidylserineMostly positive
“within 10-15 minutes if I'm feeling more down to Earth and relaxed...Over the last three weeks, I have seldom had these nervous thought loops.”Source discussion ↗
TurmericMixed
“I have an autoimmune condition that causes chronic pain and while it doesn’t eliminate the pain, I noticed an overall reduction in the intensity day to day.”Source discussion ↗
TurmericMixed
“I’ve tried physical therapy, swimming, exercises, omega-3, turmeric, and other anti-inflammatory stuff—nothing seems to help.”Source discussion ↗
TurmericMixed
“Whenever I add raw Turmeric & Ginger to my stack, I feel any existing brain fog disappear within 15 minutes... That's very unlikely that chewing on turmeric would affect you so strongly and so quickly.”Source discussion ↗
TurmericMixed
“Turmeric and Magnesium make me feel like absolute shit if I take them before sunset.”Source discussion ↗
TianeptineMostly positive
“It has really improved the quality of my life, more than anything else I have taken.”Source discussion ↗
TianeptineMostly positive
“it made my head foggy and made me more anxious. Noticed no improvement in mood.”Source discussion ↗
TianeptineMostly positive
“I take 15mg 3x daily, and it keeps me out of depression and in a good mood. It also helps me focus in class more.”Source discussion ↗
TianeptineMostly positive
“I was able to successfully quit using low doses of tianeptine. But be careful as that can be an even worse addiction.”Source discussion ↗
CistancheMostly positive
“Cistanche extract increases my drive, energy and vigor. It makes me want to attack life. I get better sleep...My work ethic has improved. My memory. my attitude towards life. Every facet of my life has been altered in a positive meaningful way.”Source discussion ↗
CistancheMostly positive
“Fucking hated it. After just a week on it my libido went non existent. It left me feeling numb, unmotivated and lazy.”Source discussion ↗
CistancheMostly positive
“Increases energy, boosts my mood, makes me feel more chilled, better libido, I feel more confident.”Source discussion ↗
CistancheMostly positive
“cistanche is the only thing I had to stop taking because it worked too well...cistanche is the only thing that made me horny all the time.”Source discussion ↗
ZMAMostly positive
“The only thing that is affordable and has seemed to help me is ZMA. I only have the anecdote that ZMA seemed to improve sex drive, sleep, dreams, erectile quality when I first t began taking it at age 18.”Source discussion ↗
ZMAMostly positive
“So then I started taking ZMA since I read it does wonders for energy and helps ensure proper sleep. I proceeded to feel worse, anhedonic and basically depressed.”Source discussion ↗
ZMAMostly positive
“supplementing ZMA, D3, creatine, sardines/DHA&EPA/other fatty fish works well for my health, sleep, and muscle gain.”Source discussion ↗
ZMAMostly positive
“my sleep quality has improved tremendously. It's hard to put into words but I feel like I'm sleeping on clouds. I'm also sleeping fewer hours but feeling more rested in the morning.”Source discussion ↗
ALAMostly positive
“I also take alcar, alpha lipoic acid, choline, and pqq, but... there is some difference with these, but not as major as with CoQ10.”Source discussion ↗
ALAMostly positive
“ALCAR+alpha lipoic acid works as well as Adderall. Actually, it's a bit better for me—it wears off more slowly and doesn't interfere with sleep the way Adderall does.”Source discussion ↗
ALAMostly positive
“ALA fixed the issue almost instantly, so I usually don't take ALCAR without the ALA.”Source discussion ↗
ALAMostly positive
“R-ALA - has shrunk keloids that I was told would never go away and helped with general over all MS body pain”Source discussion ↗
PsilocybinMostly positive
“Mushrooms make me a better husband and a better human all around. Sometimes I don’t feel the urge to have sex while I’m on a dose, but I feel much more connected afterward. Low dose is definitely an aphrodisiac in my experience.”Source discussion ↗
PsilocybinMostly positive
“doing shrooms helped a lot. I felt really peaceful...This slowly went away, and was gone the next day.”Source discussion ↗
PsilocybinMostly positive
“I also micro dose psilocybin on and off and macro dose once in awhile. This definitely helps with my overall well-being and mood.”Source discussion ↗
PsilocybinMostly positive
“The psilocybin just made my mind quieter and allowed me to focus on one thing at a time. Its also helped me just stay in a positive mood which helped my anxiety.”Source discussion ↗
St. John's WortMixed
“St. John's Wort, Passion Flower, Hops, and Skullcap. My sleep improved with those.”Source discussion ↗
St. John's WortMixed
“even the nootropics that some communities swear by did nothing for me (some that come to mind - racetams, tyrosine/NALT, NAC, methylated B vitamins...”Source discussion ↗
St. John's WortMixed
“I dabbled with 5-HTP ... and St. John's Wort ... and found them to have some nice anti-anxiety / sedating effects.”Source discussion ↗
St. John's WortMixed
“I am taking Saint John's Wort and Bacopa now to modulate my serotonin system, as well as trimethylglycine to help boost catecholamine production. That is helping a lot.”Source discussion ↗
Lithium OrotateMostly positive
“The lithium is absolutely curbing my mania... My social anxiety is 100% gone when I take lithium orotate.”Source discussion ↗
Lithium OrotateMostly positive
“Been taking 10-20 mg for a week or so... my mood is more stable. Rumination is not really there... Highly recommend... Ended up getting sexual dysfunction from it, stopped it.”Source discussion ↗
Lithium OrotateMostly positive
“I take 5mg LiOr every morning upon waking for ADHD, and I've experienced nothing but massive benefits...Many people complain about lethargy and brain fog at these doses.”Source discussion ↗
Lithium OrotateMostly positive
“Mood has increased, depression is decreased and anxiety no longer exists in my life. It has been a miracle drug for me.”Source discussion ↗