PlainPill

Tamoxifen vs Zinc for hormones

Short answer: For hormones, more users report improvement with Tamoxifen — 98% of 49 reports, versus 88% of 94 for Zinc.

Tamoxifen has 479 meta-analyses and 1,597 randomized trials on PubMed; Zinc has 220 and 555.

Based on 298 reports about Tamoxifen and 1,594 about Zinc. Not medical advice.

Tamoxifen
Medication
Zinc
Supplement
Users say it helped64%helped75 reports · medium confidence59%helped510 reports · high confidence
Verdict
Mostly positive
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs479 / 1,597220 / 555
Mainly used for
Hormones
% reporting improvement
98% (49)88% (94)
Libido
% reporting improvement
57% (7)90% (120)
Sleep
% reporting improvement
—84% (76)
Mood
% reporting improvement
0% (2)81% (68)
Energy
% reporting improvement
100% (5)74% (57)
Common side effectsfatigue, depression, low libido, headachenausea, stomach issues, vomiting, copper deficiency
Typical dose reportedNot listed75 mg
Tamoxifen
Latest review conclusion

5 years of adjuvant tamoxifen safely reduces 15-year risks of breast cancer recurrence and death. ER status was the only recorded factor importantly predictive of the proportional reductions. Hence, the absolute risk reductions produced by tamoxifen depend on the absolute breast cancer risks (after any chemotherapy) without tamoxifen.

Lancet, 2011 ↗
What a user said
“This is now 2nd day on nolva and I swaer my balls are about back to normal. Energy is a bit better”
Full Tamoxifen profile →
Zinc
Latest review conclusion

Acne patients have decreased serum zinc levels. Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment.

Dermatol Ther, 2020 ↗
What a user said
“I had actual energy in the mornings for the first time I could remember.”
Full Zinc profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate