PlainPill

NAC vs Zinc for immunity

Short answer: For immunity, more users report improvement with NAC — 100% of 33 reports, versus 86% of 28 for Zinc.

NAC has 387 meta-analyses and 767 randomized trials on PubMed; Zinc has 220 and 555.

Based on 1,575 reports about NAC and 1,257 about Zinc. Not medical advice.

NAC
Supplement
Zinc
Supplement
User score4942
Verdict
Mixed
Mostly positive
Positive
of reports that state an outcome
55%61%
Reports1,5751,257
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs387 / 767220 / 555
Mainly used for
Weight loss
% reporting improvement
67% (3)100% (3)
Appetite
% reporting improvement
90% (29)33% (3)
Focus
% reporting improvement
81% (151)62% (26)
Energy
% reporting improvement
74% (69)71% (51)
Sleep
% reporting improvement
71% (41)82% (68)
Anxiety
% reporting improvement
90% (246)72% (29)
Mood
% reporting improvement
65% (257)80% (61)
Memory
% reporting improvement
77% (13)20% (5)
Performance
% reporting improvement
75% (8)90% (20)
Recovery
% reporting improvement
86% (14)86% (7)
Pain & inflammation
% reporting improvement
86% (28)56% (9)
Digestion
% reporting improvement
72% (18)0% (2)
Libido
% reporting improvement
29% (7)88% (95)
Hormones
% reporting improvement
88% (8)89% (63)
Blood sugar
% reporting improvement
100% (3)—
Heart & lipids
% reporting improvement
67% (12)50% (2)
Skin & hair
% reporting improvement
89% (18)81% (31)
Immunity
% reporting improvement
100% (33)86% (28)
Longevity
% reporting improvement
100% (7)—
Common side effectsanhedonia, fatigue, stomach issues, depressionnausea, fatigue, stomach issues, copper deficiency
Typical dose reportedas neededdaily
NAC
Latest review conclusion

Taken together, these preliminary findings suggest that dietetic approaches might be included as part of BD treatment. Also considering the high risk of metabolic disorders in individuals with BD, they should be encouraged to choose healthy dietary lifestyles, including daily intake of fruits, vegetables, seafood and whole grains.

Nutr Neurosci, 2023 ↗
What a user said
“When I get wired up with mania, anxiety, insomnia. I usually take methylfolate and NAC.”
Full NAC profile →
Zinc
Latest review conclusion

Acne patients have decreased serum zinc levels. Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment.

Dermatol Ther, 2020 ↗
What a user said
“I also take D3, garlic and zinc that have proven effect in boosting immune system”
Full Zinc profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate