PlainPill

Tamoxifen vs Testosterone for hormones

Short answer: For hormones, more users report improvement with Tamoxifen — 98% of 49 reports, versus 91% of 101 for Testosterone.

Tamoxifen has 479 meta-analyses and 1,597 randomized trials on PubMed; Testosterone has 75 and 125.

Based on 298 reports about Tamoxifen and 924 about Testosterone. Not medical advice.

Tamoxifen
Medication
Testosterone
Medication
Users say it helped64%helped75 reports · medium confidence76%helped425 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs479 / 1,59775 / 125
Mainly used for
Performance
% reporting improvement
50% (2)98% (180)
Hormones
% reporting improvement
98% (49)91% (101)
Mood
% reporting improvement
0% (2)89% (117)
Energy
% reporting improvement
100% (5)93% (88)
Libido
% reporting improvement
57% (7)90% (78)
Common side effectsfatigue, depression, low libido, headachesuppression, hair loss, acne, water retention
Typical dose reportedNot listedNot listed
Tamoxifen
Latest review conclusion

5 years of adjuvant tamoxifen safely reduces 15-year risks of breast cancer recurrence and death. ER status was the only recorded factor importantly predictive of the proportional reductions. Hence, the absolute risk reductions produced by tamoxifen depend on the absolute breast cancer risks (after any chemotherapy) without tamoxifen.

Lancet, 2011 ↗
What a user said
“This is now 2nd day on nolva and I swaer my balls are about back to normal. Energy is a bit better”
Full Tamoxifen profile →
Testosterone
Latest review conclusion

The guidelines also provide recommendations regarding identification of patients, dosing, monitoring, and follow-up. This Practice Pearl will discuss evidence-based testosterone therapy for management of HSDD in postmenopausal women.

Menopause, 2023 ↗
What a user said
“Feel the best I've ever felt in my life. TRT and peptides have been game changers for me!”
Full Testosterone profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate