PlainPill

Vitamin C vs Zinc for immunity

Short answer: For immunity, users rate them about the same: 88% report improvement with Vitamin C (25 reports) and 86% with Zinc (28 reports).

Vitamin C has 738 meta-analyses and 2,072 randomized trials on PubMed; Zinc has 220 and 555.

Based on 715 reports about Vitamin C and 1,264 about Zinc. Not medical advice.

Vitamin C
Supplement
Zinc
Supplement
User score4442
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
68%61%
Reports7151,264
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs738 / 2,072220 / 555
Mainly used for
Weight loss
% reporting improvement
100% (3)100% (3)
Appetite
% reporting improvement
—33% (3)
Focus
% reporting improvement
67% (9)62% (26)
Energy
% reporting improvement
100% (27)71% (51)
Sleep
% reporting improvement
71% (14)82% (68)
Anxiety
% reporting improvement
92% (13)73% (30)
Mood
% reporting improvement
86% (21)80% (61)
Memory
% reporting improvement
80% (5)20% (5)
Performance
% reporting improvement
25% (4)90% (20)
Recovery
% reporting improvement
100% (8)86% (7)
Pain & inflammation
% reporting improvement
79% (14)56% (9)
Digestion
% reporting improvement
75% (4)0% (2)
Libido
% reporting improvement
100% (2)88% (95)
Hormones
% reporting improvement
100% (4)89% (63)
Heart & lipids
% reporting improvement
75% (4)50% (2)
Skin & hair
% reporting improvement
96% (24)81% (32)
Immunity
% reporting improvement
88% (25)86% (28)
Longevity
% reporting improvement
100% (3)—
Common side effectsstomach issues, kidney stones, insomnia, bone painnausea, fatigue, stomach issues, copper depletion
Typical dose reported2000 mg / dailydaily
Vitamin C
Latest review conclusion

The failure of vitamin C supplementation to reduce the incidence of colds in the general population indicates that routine vitamin C supplementation is not justified, yet vitamin C may be useful for people exposed to brief periods of severe physical exercise. Regular supplementation trials have shown that vitamin C reduces the duration of colds, but this was not replicated in the few therapeutic trials that have been carried out. Nevertheless, given the consistent effect of vitamin C on the duration and severity of colds in the regular supplementation studies, and the low cost and safety, it m

Cochrane Database Syst Rev, 2013 ↗
What a user said
“I know people say you get enough vitamin C from diet but I feel and look better when I supplement it.”
Full Vitamin C profile →
Zinc
Latest review conclusion

Acne patients have decreased serum zinc levels. Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment.

Dermatol Ther, 2020 ↗
What a user said
“I had actual energy in the mornings for the first time I could remember.”
Full Zinc profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate