Tamoxifen vs Vitamin D for hormones
Short answer: For hormones, more users report improvement with Tamoxifen — 98% of 49 reports, versus 91% of 75 for Vitamin D.
Tamoxifen has 479 meta-analyses and 1,597 randomized trials on PubMed; Vitamin D has 3,251 and 4,560.
Based on 298 reports about Tamoxifen and 3,058 about Vitamin D. Not medical advice.
| Tamoxifen Medication | Vitamin D Supplement | |
|---|---|---|
| Users say it helped | 64%helped75 reports · medium confidence | 67%helped1,101 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 479 / 1,597 | 3,251 / 4,560 |
| Mainly used for | ||
| Mood % reporting improvement | 0% (2) | 88% (393) |
| Energy % reporting improvement | 100% (5) | 87% (255) |
| Hormones % reporting improvement | 98% (49) | 91% (75) |
| Sleep % reporting improvement | — | 52% (119) |
| Immunity % reporting improvement | — | 98% (94) |
| Common side effects | fatigue, depression, low libido, headache | insomnia, anxiety, hypercalcemia, nausea |
| Typical dose reported | Not listed | 10,000-20,000 IU / daily |
5 years of adjuvant tamoxifen safely reduces 15-year risks of breast cancer recurrence and death. ER status was the only recorded factor importantly predictive of the proportional reductions. Hence, the absolute risk reductions produced by tamoxifen depend on the absolute breast cancer risks (after any chemotherapy) without tamoxifen.
Lancet, 2011 ↗“This is now 2nd day on nolva and I swaer my balls are about back to normal. Energy is a bit better”
These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.
Obes Rev, 2015 ↗“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate