LGD-4033 vs Tadalafil for performance
Short answer: For performance, more users report improvement with Tadalafil — 97% of 61 reports, versus 90% of 178 for LGD-4033.
LGD-4033 has 1 meta-analyses and 1 randomized trials on PubMed; Tadalafil has 120 and 347.
Based on 491 reports about LGD-4033 and 214 about Tadalafil. Not medical advice.
| LGD-4033 SARM | Tadalafil Medication | |
|---|---|---|
| User score | 54 | 65 |
| Verdict | Mixed | Mostly positive |
| Positive of reports that state an outcome | 50% | 78% |
| Reports | 491 | 214 |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 1 / 1 | 120 / 347 |
| Mainly used for | ||
| Weight loss % reporting improvement | 94% (33) | — |
| Appetite % reporting improvement | 60% (5) | — |
| Focus % reporting improvement | 50% (4) | 88% (8) |
| Energy % reporting improvement | 45% (22) | 100% (6) |
| Sleep % reporting improvement | 17% (6) | 100% (4) |
| Anxiety % reporting improvement | 0% (3) | 75% (4) |
| Mood % reporting improvement | 25% (24) | 100% (9) |
| Performance % reporting improvement | 90% (178) | 97% (61) |
| Recovery % reporting improvement | 100% (13) | 100% (6) |
| Pain & inflammation % reporting improvement | 0% (5) | 100% (2) |
| Digestion % reporting improvement | 50% (2) | — |
| Libido % reporting improvement | 19% (27) | 91% (82) |
| Hormones % reporting improvement | 4% (48) | 100% (3) |
| Blood sugar % reporting improvement | — | 100% (2) |
| Heart & lipids % reporting improvement | 0% (12) | 100% (17) |
| Skin & hair % reporting improvement | 0% (3) | — |
| Longevity % reporting improvement | — | 100% (2) |
| Common side effects | suppression, water retention, fatigue, stomach issues | headache, stuffy nose, heartburn, lower back |
| Typical dose reported | Not listed | 2.5-5 mg / daily or 5-10 mg every other day |
SARMs have a positive effect on physical performance and body composition and are associated with moderate rates of mild to moderate adverse effects (AEs) and a low rate of severe AEs.
Clin Endocrinol (Oxf), 2025 ↗“I've taken LDG-4033 and Ostarine from Ceretropic and noticed slight psychoactive effects from both, immediately (within 30 minutes after dosing).”
Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence. Furthermore, patients and their partners prefer tadalafil to sildenafil. Hence, tadalafil may be a better choice for ED treatment.
Int Urol Nephrol, 2017 ↗“After a week of 2.5 mg twice a day, this is my favourite drug ever. My brain fog has gone...My mood is so much better, similar to an SSRI but without the flat feeling.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate