Agmatine vs Arginine for performance
Short answer: For performance, more users report improvement with Agmatine — 97% of 35 reports, versus 67% of 9 for Arginine.
Agmatine has 2 meta-analyses and 6 randomized trials on PubMed; Arginine has 585 and 1,869.
Based on 790 reports about Agmatine and 70 about Arginine. Not medical advice.
| Agmatine Supplement | Arginine Supplement | |
|---|---|---|
| Users say it helped | 70%helped316 reports · high confidence | 40%helped30 reports · medium confidence |
| Verdict | Mostly positive | Mixed |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 2 / 6 | 585 / 1,869 |
| Mainly used for | ||
| Mood % reporting improvement | 89% (150) | — |
| Anxiety % reporting improvement | 89% (121) | — |
| Sleep % reporting improvement | 84% (44) | — |
| Performance % reporting improvement | 97% (35) | 67% (9) |
| Focus % reporting improvement | 76% (33) | — |
| Common side effects | drowsiness, vivid dreams, stomach issues, dizziness | drowsiness, cold sores, fever blisters, diarrhea |
| Typical dose reported | 1.5 g / before workout | 2.6 g |
Levels of food-derived monoamine oxidase inhibitors and anti-bacterial compounds, the potential modulators of ADAS-bacteria growth and biogenic amine production, were altered in C&A versus NNI. ADAS is attributable to potentially modifiable risk factors of AD associated diseases.
J Alzheimers Dis, 2019 ↗“I stopped thinking about frequently killing myself, stopped going down negative thought pattern spirals, and I can actually enjoy video games for once.”
Nutritional intervention with perioperative immunonutrition in patients with HAN and GI cancers significantly reduced total postoperative complications and infectious complications.
Ann Surg, 2024 ↗“2.6g of Arginine and Lysine together was found in a randomised control trial to significantly lower cortisol and anxiety... Anecdotally, this has worked really well for me too”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate