People mainly take Arginine for libido, performance. Based on 22 first-hand reports and 585 meta-analyses & systematic reviews in the medical literature. Ranked #258 of 1,974 overall.
Of reports that state an outcome, 40% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Nutritional intervention with perioperative immunonutrition in patients with HAN and GI cancers significantly reduced total postoperative complications and infectious complications.
PubMed 37882375 ↗Conclusion: Regarding T-cell lymphocytes, a slight decrease was observed, although it failed to reach significance (MD: -0.16, 95% CI: -0.33, 0.01, p = 0.07). Conclusion: The wound healing might be enhanced in one or at various stages by nutritional supplementation in the right dose.
PubMed 34444657 ↗Conclusion: The benefits of nutritional interventions with various compositions for pressure ulcer prevention and treatment are uncertain. There may be little or no difference compared to standard nutrition or placebo. Nutritional supplements may not increase gastrointestinal side effects, but the evidence is very uncertain. Larger studies with similar nutrient compositions would reduce these uncertainties. No study investigated the effects of special diets (e.g. protein-enriched diet, vegetarian diet) on pressure ulcer incidence and healing.
PubMed 38345088 ↗Conclusion: Based on the scoring system, 2 (8%) supplements matched with the cluster of higher expected efficacy, 3 (12%) with the lower efficacy cluster and 20 (80%) matched with the criterion of no expected efficacy. DSs marketed in Italy are usually blends of many substances that are frequently employed at a negligible dose or without any evidence.
PubMed 37686709 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“Has anyone tried Arginine yet ? If so how do you cycle it etc.”
“Arginine, ginseng, agmatine, ginkgo biloba, zinc, DHEA (caution but super effective for me)”
“Arginine: important in enos mediated vasodilation buochemically, not much evidence clinicaly for benefit.”
“Arginine and other vasodilators are tried and true supplements for erection health.”
“Citrulline is the better option over arginine for NO for blood flow.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate