Agmatine vs Citrulline for performance
Short answer: For performance, users rate them about the same: 97% report improvement with Agmatine (35 reports) and 100% with Citrulline (31 reports).
Agmatine has 2 meta-analyses and 6 randomized trials on PubMed; Citrulline has 51 and 258.
Based on 790 reports about Agmatine and 157 about Citrulline. Not medical advice.
| Agmatine Supplement | Citrulline Supplement | |
|---|---|---|
| Users say it helped | 70%helped316 reports · high confidence | 84%helped58 reports · medium confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 2 / 6 | 51 / 258 |
| Mainly used for | ||
| Mood % reporting improvement | 89% (150) | — |
| Anxiety % reporting improvement | 89% (121) | — |
| Performance % reporting improvement | 97% (35) | 100% (31) |
| Sleep % reporting improvement | 84% (44) | — |
| Libido % reporting improvement | 93% (15) | 90% (20) |
| Common side effects | drowsiness, vivid dreams, stomach issues, dizziness | erectile dysfunction, tooth erosion, tooth enamel, gerd |
| Typical dose reported | 1.5 g / before workout | 1 g |
Levels of food-derived monoamine oxidase inhibitors and anti-bacterial compounds, the potential modulators of ADAS-bacteria growth and biogenic amine production, were altered in C&A versus NNI. ADAS is attributable to potentially modifiable risk factors of AD associated diseases.
J Alzheimers Dis, 2019 ↗“I stopped thinking about frequently killing myself, stopped going down negative thought pattern spirals, and I can actually enjoy video games for once.”
Supplementation of some but not all micronutrients may benefit cardiometabolic health. This study highlights the importance of micronutrient diversity and the balance of benefits and risks to promote and maintain cardiovascular health in diverse populations. (Antioxidant Supplementation in the Prevention and Treatment of Cardiovascular Diseases; CRD42022315165).
J Am Coll Cardiol, 2022 ↗“try all the standard vasodilators - citrulline and agmatine helped me a lot.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate