PlainPill

What people actually say

1,296 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
DihexaMostly positive
“I've taken it three times, all orally. It's easily the most profound substance i've tried yet...Better memory and general retention, greater plasticity...improved physical performance”
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DihexaMostly positive
“fish oil psilocybin dihexa and fast for at least 24 hrs once per week... these are the things i feel were absolutely critical in my recovery.”
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DihexaMostly positive
“some peptides like dihexa, Cerebrolysin, selank, semax, and Retatrutide also helped my recovery”
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GHRP-6Mostly positive
“GHRP-6/2 or Ipamorelin is way better and was side effect free for me.”
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GHRP-6Mostly positive
“I don't feel any of them worsen sleep except for ghrp 2 and 6 because they can induce hunger.”
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GHRP-6Mostly positive
“GHRP6 600mcg subq ... holy I feel freaking amazing the next day. Waaaay less anxiety the next day, I feel really restored. Amazing for sleep, both deep and REM”
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GHRP-6Mostly positive
“ghrp2/6 when I was 23-25...gives me great hunger and helps to recover after workouts”
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IbuprofenMostly positive
“I've always had a positive response to ibuprofen and would take it morning and night if it wasn't for the side effects and agmatine provides the same anti-depressant effects of ibuprofen.”
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IbuprofenMostly positive
“I take 1600mgs of advil and a 100mgs of zinc supplements a night. Have noticed absolutely nothing. Except better sleep.”
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IbuprofenMostly positive
“I find curcumin works just as well, if not better, than ibuprofen.”
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IbuprofenMostly positive
“I tried paracetamol, ibuprofen, tramadol(all painkillers) and methyl salicylate to decrease inflammation prescribed by my doctor but nothing is working.”
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BenfotiamineMostly positive
“A combination of benfotiamine and sulbutiamine with magnesium greatly improved my erratic movements (twitching, ataxia, shaking hands, etc.) and energy levels.”
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BenfotiamineMostly positive
“March I added 80mg benfo. Too much too quick. April 9th...took additional 80mg benfo accidentally...Felt off- all day.”
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BenfotiamineMostly positive
“This treats my ADHD symptoms almost completely. It has all the positive mental/cognitive effects without any of the negative side effects.”
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BenfotiamineMostly positive
“today i introduced Mega benfo from life extension and it was like limitless pill, my vision brightened, my apathy roofed and i felt like i could conquer the world”
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“when i take benzos, suddenly all my brain issues/brain fog/memory problems/focus problems seem resolved. i can calmly focus on things, i recall things more easily, everything seems just right.”
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“Nothing really ever helped besides the benzodiazepines, but I’m well aware of how they will turn on you within months.”
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“Helps with anxiety but makes me depressive as hell, I will probably end up crying if I take one.”
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“Benzos are great for the 'I literally have zero anxiety about anything' feeling, but they make me sleepy.”
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P21Mostly positive
“I have been taking 1mg of p21 for about two weeks, and my concentration has improved markedly but my memory has improved even more so.”
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P21Mostly positive
“P21 was a strange combination of unpleasant stimulation and lethargy, which had a pretty negative impact on my sleep.”
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P21Mostly positive
“It had more of an activating feel in my experience. Somewhat anxiogenic at times even.”
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P21Mostly positive
“I can personally attest to a lessened overall anxiety level due to both P21 and Semax in combination”
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Chamomile TeaMostly positive
“Mild as it sounds chamomile tea works wonders for me, even when dealing with withdrawals that worsens my insomnia.”
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Chamomile TeaMostly positive
“I've tried reducing my screen time early, drinking chamomile tea, and taking magnesium before bed. None of it has helped.”
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Chamomile TeaMostly positive
“I find chamomile helps me a lot before bed. Also helps with my GERD a bit.”
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Chamomile TeaMostly positive
“Things I've tried that didn't work: valerian root, magnesium glycinate, theanine, chamomile tea, cannabis indica (no effect, either negative or positive, on sleep)”
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ClonidineMostly positive
“Clonidine really helped me when I was getting off benzos. I still use it now as a replacement for when I get anxiety.”
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ClonidineMostly positive
“it made me feel dizzy, sleepy, cognitively much worse during the day...felt like the two medications were fighting for supremacy.”
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ClonidineMostly positive
“For acute anxiety or panic attacks I take Clonidine at 100mcg. It also makes an excellent sleeping pill.”
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ClonidineMostly positive
“I get some sleep now with .1mg clonidine and 25 mg atarax combined but it's often short and really broken up.”
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Cold ShowerMostly positive
“having a cold shower in the morning made a difference on my energy levels and focus throughout the day.”
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Cold ShowerMostly positive
“I did a quick 2-3 minute cold shower before bed and it doubled my deep sleep duration. I have no idea why and it might not be applicable to everyone.”
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Cold ShowerMostly positive
“For me it’s great increased my deep sleep according to Oura. Average has gone from 1h per night to roughly 1h30min consistently.”
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Cold ShowerMostly positive
“my energy/productivity/coherence index parameters... shoot to the skies after a cold shower.”
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TherapyMostly positive
“For me it was therapy that helped. I had some kind of guilt issue from trauma I didn’t even remember until therapy.”
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TherapyMostly positive
“Started doing some therapy and an SSRI, and saw huge improvement in all my symptoms.”
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TherapyMostly positive
“NAC and other supplements, alongside weekly therapy and a wholesale-healthy lifestyle, have helped nurse me back to health.”
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TherapyMostly positive
“I tried everything in the natural toolkit: L theanine, magnesium, NAC, ashwagandha, CBD, therapy, meditation you name it... But nothing really touched the core issue.”
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LithiumMixed
“my doctor put me on low dose lithium a couple months ago... it has changed my life.”
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User reports — what people say about supplements — PlainPill