PlainPill

What people actually say

1,588 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
NiacinMostly positive
“If you over methylate, niacin may also help you. Binds to free methyl groups... It's how I fixed my heart palpitations after taking methylsulfonymethan.”
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NiacinMostly positive
“Been taking Niacin, but other than the flush, I've found it makes me feel kinda irritable after taking it and my stomach doesn't feel great.”
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NiacinMostly positive
“I take niacin daily and have noticed big improvements in mental clarity / focus.”
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NiacinMostly positive
“Had bad flushing w/ the niacin. Felt like I was on fire, massive blotching covered entire body.”
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TadalafilMostly positive
“After a week of 2.5 mg twice a day, this is my favourite drug ever. My brain fog has gone...My mood is so much better, similar to an SSRI but without the flat feeling.”
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TadalafilMostly positive
“I use it sporadically as a preworkout, 5mg before gym, gets a nice pump going - I always get a stuffy nose and that's about it from side effects that Ive noticed.”
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TadalafilMostly positive
“It's probably the only drug I've ever taken that's improved my overall mood and impacted my mental health positively. People say it's because the improved blood flow in the brain.”
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TadalafilMostly positive
“I take it for neuropathy. It’s solved about 95% of the tingling... Also fixed ED. I’m cutting the pills in half so it’s 2.5mg a day but works wonders.”
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IronMostly positive
“I supplemented with sublingual b12 and iron and daily electrolytes and I'm feeling much better.”
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IronMostly positive
“I have noticed quite a few supplements 'especially' herb based Iron supplements not working anymore, when before they used to.”
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IronMostly positive
“Even though that is no where near 200ug, I'm noticing that my fatigue and mood is much better. My skin is clearer, and my period has become slightly less heavy.”
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IronMostly positive
“I had something similar, my issue was low ferritin. I took iron supps and I’m feeling better than I have in years.”
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PolygalaMostly positive
“I also take 100mg of Polygala 3x a day sublingual. It helps with recurring bad thoughts, and focus...helps with overall mood and sleep.”
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PolygalaMostly positive
“I’ve found Polygala was much better for focus whereas agmatine was way better for my mood.”
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PolygalaMostly positive
“Polygala alone (for me): quieter mind, slightly clearer thinking, but also slightly 'flattened' feeling...but in this combo it suddenly feels like the foundation that makes everything else work better.”
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PolygalaMostly positive
“It immediately rid me of depression/anhedonia. My focus, energy, and memory all seem to have improved...I feel like the best version of myself.”
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Milk ThistleMostly positive
“Adrafinil and milk thistle is my current best solution...Milk thistle helps for the hepatoxicity (as you know)”
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Milk ThistleMostly positive
“Nothing much happened. I still had those problems after trying all that nootropics and supplements.”
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Milk ThistleMostly positive
“Milk thistle can with some people cause Hypothyroidism... I had to quit taking I started gaining weight and my thyroid was swollen and hurt.”
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Milk ThistleMostly positive
“I have improved taking milk thistle which helps my liver heal and to detoxify toxins.”
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“I know pregnenalone helped me with that anxiety... 25mg a day is wonderful.”
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“Now it's like 90% fixed by pregnenolone. However, I been taking around 10 to 20 mg this is the sweet spot for me if I take anymore I get the opposite reaction such as more fatigue and tiredness.”
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“I've been taking pregnenolone, dhea, and tongkhat ali and it helps keep my mind straight while living alone, working alone.”
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“I've never felt more comfortable in my own skin, more calm, or stable. Things just feel right. But: Definitely not a keeper for me. Either no effect or I get more jittery/anxious.”
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L-TryptophanMostly positive
“L-Tryptophan has given me the most relaxation / anti-anxiety out of the aminos I've tried.”
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L-TryptophanMostly positive
“I've felt like I'm on a microdose of LSD that's slightly too large lol. I feel that unique uncomfortable feeling where my atoms feel like they're vibrating a bit too quickly.”
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L-TryptophanMostly positive
“L-tryptophan has been a game changer for my seasonal depression... Whenever I start to get that feeling of 'what's the point' I pop 2 of ND's L-tryptophan and feel so much better.”
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L-TryptophanMostly positive
“L-tryptophan makes me sleep deeper, and I wake up feeling more content.”
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“I really like lemon balm especially if combined with valerian root! Helps me sleep and relax at night.”
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“Valerian tea only works about once or twice a month, any more frequent and I get zero effect...I only dream when I take Valerian Root...I definitely enjoy the dreams.”
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“I've tried valerian root capsules. Those did not help me staying a sleep.”
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“Valerian root are my own little 'fuck you's to the racing thoughts/inability to sleep.”
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KannaMostly positive
“Kanna tablets. Dissolve under the tongue...I can't sing Kannas praises enough. It's the instant cure for my brain fog, lack of energy, and lack of motivation.”
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KannaMostly positive
“kanna works well for some people. But it doesn't work well for me and makes me depressed.”
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KannaMostly positive
“I feel so happy when it kicks in...great product and prefer it over LM, recommending to my friends!”
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KannaMostly positive
“I'm now starting to use things like 5-HTP, Kanna extract, etc. again. Way better.”
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L-CitrullineMostly positive
“Something I found that makes my meds work way better is Citrulline 2g + Arginine 2g twice daily.”
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L-CitrullineMostly positive
“within hours I feel amazing! Aches pretty much disappeared and I have energy levels I hadn't felt in several months.”
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L-CitrullineMostly positive
“I noticed a MARKED improvement in cognitive abilities, feeling witty with ideas in my head, ambitions to do or think about things, less brain fog and also greatly improved mood.”
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L-CitrullineMostly positive
“I'd say 95% of them are gone the few that remain I notice every few days if I try to focus on them they are fainter and fainter.”
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