Conclusion: In addition, this meta-analysis focuses on the efficacy of CBD in treating anxiety disorders such as generalized anxiety disorder (GAD), social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD). However, caution should be exercised in interpreting our findings due to the limited size of the clinical sample, and additional trials ought to be carried out if deemed necessary.
PubMed 38924898 ↗CBD
People mainly take CBD for anxiety, sleep, mood. Based on 220 first-hand reports and 286 meta-analyses & systematic reviews in the medical literature. Ranked #45 of 1,974 overall.
Of reports that state an outcome, 59% are positive.
What CBD does, according to users
Of the people who reported each effect, the share who said it got better.
6 more with fewer than 3 reports
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: The efficacy assessment, associated to the level of quality of each trial, presented an evident clinical analgesic efficacy for omega-3-enriched diets, omega-3 supplements and cannabidiol (to a lesser degree). Our analyses showed a weak efficacy of collagen and a very marked non-effect of chondroitin-glucosamine nutraceuticals, which leads us to recommend that the latter products should no longer be recommended for pain management in canine and feline osteoarthritis.
PubMed 36142319 ↗Conclusion: Cannabinoids are effective therapeutics for several medical indications if their specific pharmacological properties are considered. We suggest that future systematic studies in the cannabinoid field should be based upon their specific pharmacology.
PubMed 35982439 ↗Conclusion: Although individual-level risk remains moderate to low and results from this study should be confirmed in future adequately powered prospective studies, the high prevalence of adolescents consuming cannabis generates a large number of young people who could develop depression and suicidality attributable to cannabis. This is an important public health problem and concern, which should be properly addressed by health care policy.
PubMed 30758486 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“if it’s legal, CBD is supposed to help with anxiety.”
“CBD (crystals 99.9%) very potent against anxiety and racing thoughts”
“What I've tried so far to increase deep sleep that hasn't helped noticeably: CBD”
“CBD”
“There are plenty of studies that have found benefit to CBD in isolation.”
Top discussions (5)
- Edibles changed my life ↗
- I am going to WAR against my INFLAMMATION. Assist me biohacking brothers. ↗
- Chronic THC use causing D1/D2 heteromer formation in the Nucleus Accumbens and Striatum, changing from functioning with dopamine to functioning with Dynorphin. ↗
- The oral bioavailability of EVERY nootropic (84+) ↗
- Propranolol made every other anti-anxiety supplement I’ve tried look like a placebo ↗
Other options for anxiety
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate