PlainPill

CBD vs Kratom for anxiety

Short answer: For anxiety, users rate them about the same: 88% report improvement with CBD (185 reports) and 91% with Kratom (108 reports).

CBD has 286 meta-analyses and 344 randomized trials on PubMed; Kratom has 18 and 5.

Based on 482 reports about CBD and 568 about Kratom. Not medical advice.

CBD
Supplement
Kratom
Substance
Users say it helped59%helped236 reports · high confidence46%helped335 reports · high confidence
Verdict
Mixed
Mixed
ResearchAResearch: StrongBResearch: Moderate
Meta-analyses / RCTs286 / 34418 / 5
Mainly used for
Anxiety
% reporting improvement
88% (185)91% (108)
Mood
% reporting improvement
85% (34)87% (142)
Energy
% reporting improvement
50% (4)84% (88)
Sleep
% reporting improvement
72% (76)75% (12)
Pain & inflammation
% reporting improvement
80% (35)94% (36)
Common side effectsbrain fog, headache, wakefulness, subdued feelingwithdrawal, dependence, addiction, tolerance
Typical dose reported30-60 mg; 54 mg / after dinner; before bed4 g / 2x daily
CBD
Latest review conclusion

In addition, this meta-analysis focuses on the efficacy of CBD in treating anxiety disorders such as generalized anxiety disorder (GAD), social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD). However, caution should be exercised in interpreting our findings due to the limited size of the clinical sample, and additional trials ought to be carried out if deemed necessary.

Psychiatry Res, 2024 ↗
What a user said
“I take it for sleeping and anxiety and it works so well, even after five years. I haven't build up any tolerance.”
Full CBD profile →
Kratom
Latest review conclusion

Based on our analysis, patients using <20 g of kratom/d could be initiated on opioid agonist therapy with 4/1 mg-8/2 mg buprenorphine-naloxone/d, while patients using kratom doses >40 g/d could be initiated with 12/3 mg-16/4 mg of buprenorphine-naloxone/day.

J Addict Med, 2021 ↗
What a user said
“Green or white Kratom powder. My productivity and overall mood have skyrocketed. I dose 4 grams once per day and it’s worked wonders.”
Full Kratom profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate