PlainPill

CBD vs Kanna for anxiety

Short answer: For anxiety, users rate them about the same: 88% report improvement with CBD (185 reports) and 88% with Kanna (42 reports).

CBD has 286 meta-analyses and 344 randomized trials on PubMed; Kanna has 8 and 0.

Based on 482 reports about CBD and 231 about Kanna. Not medical advice.

CBD
Supplement
Kanna
Supplement
Users say it helped59%helped236 reports · high confidence77%helped102 reports · high confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongBResearch: Moderate
Meta-analyses / RCTs286 / 3448 / 0
Mainly used for
Anxiety
% reporting improvement
88% (185)88% (42)
Mood
% reporting improvement
85% (34)94% (84)
Sleep
% reporting improvement
72% (76)100% (2)
Pain & inflammation
% reporting improvement
80% (35)—
Focus
% reporting improvement
83% (12)100% (6)
Common side effectsbrain fog, headache, wakefulness, subdued feelingdrowsiness, appetite suppression, brain fog, agitation
Typical dose reported30-60 mg; 54 mg / after dinner; before bed300mg sublingual
CBD
Latest review conclusion

In addition, this meta-analysis focuses on the efficacy of CBD in treating anxiety disorders such as generalized anxiety disorder (GAD), social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD). However, caution should be exercised in interpreting our findings due to the limited size of the clinical sample, and additional trials ought to be carried out if deemed necessary.

Psychiatry Res, 2024 ↗
What a user said
“I take it for sleeping and anxiety and it works so well, even after five years. I haven't build up any tolerance.”
Full CBD profile →
Kanna
Latest review conclusion

Additional top genes influence stress, immune, fear and threat-related processes, previously hypothesized to underlie PTSD neurobiology. These findings strengthen our understanding of neurobiological systems relevant to PTSD pathophysiology, while also opening new areas for investigation.

Nat Genet, 2024 ↗
What a user said
“Kanna tablets. Dissolve under the tongue...I can't sing Kannas praises enough. It's the instant cure for my brain fog, lack of energy, and lack of motivation.”
Full Kanna profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate