Melanotan Ii vs Omega-3 for skin & hair
Short answer: For skin & hair, users rate them about the same: 88% report improvement with Melanotan Ii (84 reports) and 90% with Omega-3 (48 reports).
Melanotan Ii has 1 meta-analyses and 1 randomized trials on PubMed; Omega-3 has 1,341 and 3,093.
Based on 186 reports about Melanotan Ii and 3,026 about Omega-3. Not medical advice.
| Melanotan Ii Peptide | Omega-3 Supplement | |
|---|---|---|
| Users say it helped | 60%helped115 reports · high confidence | 69%helped968 reports · high confidence |
| Verdict | Mixed | Mostly positive |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 1 / 1 | 1,341 / 3,093 |
| Mainly used for | ||
| Mood % reporting improvement | 40% (5) | 86% (289) |
| Focus % reporting improvement | — | 85% (172) |
| Skin & hair % reporting improvement | 88% (84) | 90% (48) |
| Pain & inflammation % reporting improvement | — | 93% (112) |
| Heart & lipids % reporting improvement | 33% (3) | 83% (108) |
| Common side effects | nausea, flushing, freckles, moles | fish burps, stomach issues, vivid dreams, fishy burps |
| Typical dose reported | Not listed | 500/250 mg / daily |
Almost all studies are in the preclinical phase. There are currently no effective clinical treatments for MC4R-deficient obese patients, although MC4R agonists are being developed and are entering phase I and II trials.
Int J Obes (Lond), 2014 ↗“I've found that getting sun within 3-12 hours will produce the desired result.”
For glycated hemoglobin, there was no significant effect in the meta-analysis. This systematic review with meta-analysis demonstrated that supplementation with omega-3 has protective effects on diabetes parameters.
Crit Rev Food Sci Nutr, 2022 ↗“I do supplement a lot of fish oil and vitamin A as retinyl palmitate though. It has really helped my depression, anxiety and ADHD and has enabled me to stop using more serious psychiatric drugs for those things.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate