PlainPill

What people actually say

10,566 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
“Bacopi, Lions Mane, Resveratrol - these help with a weird deep prickly headache I get when I am suffering from lack of sleep and too much stimulation.”
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“Resveratrol did initially but when I started keto (high fat, low carb) I noticed not so much after.”
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“I've used resveratrol topical creams and they were exceptionally effective at increasing testosterone. I could feel my testosterone was elevated...My workouts were more intense, I would be crazy horny.”
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“It has helped with the little bit of gyn i got after that.”
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“I use the Reservatrol every other day mixed with my olive oil based omega supplement. I've never seen something create such a noticeable difference in reducing my pain”
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“I've started taking vitamin d, niacin, and resveratrol which I feel has improved my energy levels”
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“the increased sirtuin activity of resveratrol is caused indirectly because of some stress to your body, and also that it blunts the benefits of exercise. I've stopped taking it for a few months now”
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“I personally take dihydromyricetin and resveratrol daily, and I feel great on them. Helps me with my allergies”
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“I feel like I have all the positives of Adderall (focus, motivation, mood increase) without any noticeable downsides. No crash, no anxiety, no cardiac issues.”
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“I woke up the next day feeling incredible! I felt light and buoyant...I felt light and buoyant. I had a strong desire to be outside in nature...my memory started to improve, my verbal fluency went up as well.”
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“Memantine (7/10): For the first few days, I felt amazing on it. I definitely felt an increased mood and decreased anxiety. Those effects subdued...”
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“Memantine 10-30mg. Helps me significantly with general anxiety and hypervigilance from cPTSD. It also just generally improves mood when used sparingly.”
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“I've been on Memantine at 10mg/day for over a month now. I can focus better, it's easier to motivate myself to get things done, and I'm procrastinating much less than I used to.”
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“I have taken MEM for depression, and I must say it worked really well, the brain fog is not unbearable and only lasted the day of the first dose.”
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“12:00 i feel a boost in mood and motivation, the motivation is normal with adderall but i belive the memantine is boosting my mood.”
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“it gives me that "don't give a fuck" type of alpha calm feeling, albeit mildly.”
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“I noticed benefits as early as 3 days of taking 10mgs daily in dived doses.”
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“The best thing that helps me is venlafaxine and memantine, but I'm currently taking a tolerance break from memantine.”
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“Used memantine to get off of kratom and it worked amazingly! But now I’m dependent on memantine.”
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“I really like Memantine and Agmatine. Both works effective in terms of treating my anxiety and anhedonia. Unfortunately they both create too many side-effects. Memantine makes euphoric and wierd.”
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“I've been testing memantine at 5 mgs for about a week. It's been pretty great so far. Calm focus, increased sex drive, a little detached.”
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“Chronically, it seems to have caused somewhat of an improvement in my symptoms and is probably the most effective thing I've tried on this list, but I'm definitely still depressed.”
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“It ruined me. My thoughts are lost i can't get my words out. I feel like an idiot. It's been over 6 months since I've stopped.”
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“Within 3, 4 days I noticed a change. Since then, I still take Adderall and Vyvanse, with Memantine as a buffer.”
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NiacinMostly positive
“If you over methylate, niacin may also help you. Binds to free methyl groups... It's how I fixed my heart palpitations after taking methylsulfonymethan.”
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NiacinMostly positive
“Been taking Niacin, but other than the flush, I've found it makes me feel kinda irritable after taking it and my stomach doesn't feel great.”
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NiacinMostly positive
“I take niacin daily and have noticed big improvements in mental clarity / focus.”
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NiacinMostly positive
“it takes close to 10 grams of niacin a day to tame my symptoms and have me feeling good.”
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NiacinMostly positive
“I've been megadosing Niacin for a couple of years and anecdotally feel like it's improving my health.”
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NiacinMostly positive
“Niacin (as nicotinic acid, no relation to nicotine) can also help with NAD (worked for me).”
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NiacinMostly positive
“Had bad flushing w/ the niacin. Felt like I was on fire, massive blotching covered entire body.”
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NiacinMostly positive
“I cured it with micro dosing mushrooms, niacin and lions mane (took about 6 months, with 4 days on, 3 days off).”
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NiacinMostly positive
“Ever since I started taking niacin daily it's greatly reduced the frequency and intensity of them, but you have to get the flushing kind.”
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NiacinMostly positive
“I've experienced a big improvement in this after taking B3 (in the form of nicotinic acid).”
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NiacinMostly positive
“I take nicotine and the B3 niacin. I think it helps with anxiety. 100mg dose.”
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NiacinMostly positive
“I saw a notable difference after a month of 250mg/day...I got sick of cutting the caplets, so I've been taking 500mg for the last 2 months.”
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NiacinMostly positive
“I have suffered from fatigue for decades, but thanks to it I feel better than ever, I take 500-1000 mg/day.”
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NiacinMostly positive
“I have been using niacin (1 gram/3 times a day) for about a month and I do notice an increase in energy when I take it.”
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NiacinMostly positive
“High doses of niacin improves blood flow and hormone production. I noticed a difference before even looking into it... I had a lower sex drive that’s been awakened by niacin”
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NiacinMostly positive
“I've also been doing a Niacin flush 1000mg, the sauna and exercising daily and plan on continuing because it has also been helping”
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