What people actually say
2,068 first-hand quotes, shortened but never edited — each links to the original discussion.
AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
ClonidineMostly positive
“it made me feel dizzy, sleepy, cognitively much worse during the day...felt like the two medications were fighting for supremacy.”Source discussion ↗
ClonidineMostly positive
“For acute anxiety or panic attacks I take Clonidine at 100mcg. It also makes an excellent sleeping pill.”Source discussion ↗
ClonidineMostly positive
“I get some sleep now with .1mg clonidine and 25 mg atarax combined but it's often short and really broken up.”Source discussion ↗
PRL-8-53Mostly positive
“On PRL-8-53 (10-20mg), my working memory is both massively improved and effortless.”Source discussion ↗
PRL-8-53Mostly positive
“I definitely feel a reduction in daily anxiety and improved focus. Socializing is much easier and seemingly more fulfilling.”Source discussion ↗
PRL-8-53Mostly positive
“I seemed to have more energy to do things. ... Concentration in video games was enhanced quite a bit.”Source discussion ↗
PRL-8-53Mostly positive
“my memory short term and long term have improved drastically thanks to prl 853 and ciltep”Source discussion ↗
Cold ShowerMostly positive
“having a cold shower in the morning made a difference on my energy levels and focus throughout the day.”Source discussion ↗
Cold ShowerMostly positive
“I did a quick 2-3 minute cold shower before bed and it doubled my deep sleep duration. I have no idea why and it might not be applicable to everyone.”Source discussion ↗
Cold ShowerMostly positive
“For me it’s great increased my deep sleep according to Oura. Average has gone from 1h per night to roughly 1h30min consistently.”Source discussion ↗
Cold ShowerMostly positive
“my energy/productivity/coherence index parameters... shoot to the skies after a cold shower.”Source discussion ↗
TherapyMostly positive
“For me it was therapy that helped. I had some kind of guilt issue from trauma I didn’t even remember until therapy.”Source discussion ↗
TherapyMostly positive
“Started doing some therapy and an SSRI, and saw huge improvement in all my symptoms.”Source discussion ↗
TherapyMostly positive
“NAC and other supplements, alongside weekly therapy and a wholesale-healthy lifestyle, have helped nurse me back to health.”Source discussion ↗
TherapyMostly positive
“I tried everything in the natural toolkit: L theanine, magnesium, NAC, ashwagandha, CBD, therapy, meditation you name it... But nothing really touched the core issue.”Source discussion ↗
LithiumMixed
“my doctor put me on low dose lithium a couple months ago... it has changed my life.”Source discussion ↗
LithiumMixed
“I'm dumber than ever on lithium... Lithium is either interphering with my Adderall or the cognitive dampening is cancelling out the focus and alertness benefits.”Source discussion ↗
LithiumMixed
“I personally used 2 - 5mg elemental lithium about twice a week ... improvement in cognitive and mood stabilization.”Source discussion ↗
LithiumMixed
“When I take 5mg of lithium orotate it gives me a feeling of apathy, but reduces my ability to experience pleasure (what is called anhedonia).”Source discussion ↗
Low Carb DietMostly positive
“I find my focus is the best on a low carb diet.”Source discussion ↗
Low Carb DietMostly positive
“When I ate low carb and ate nuts and things like that my energy for that day was significantly lower”Source discussion ↗
Low Carb DietMostly positive
“my brain works like 40-50% better on low carb, ESPECIALLY when I eat meat. Verbal fluency, word recall, short-term and long-term memory it's all at much better level.”Source discussion ↗
Low Carb DietMostly positive
“Supplements and medication help short-term, but never long-term...eating fewer carbs and meditating at least 20 minutes a day really helps me feel better overall without a crash.”Source discussion ↗
DynamineMostly positive
“I think Dynamine is the only truly sleep-safe short term stim for evening among ND range of products.”Source discussion ↗
DynamineMostly positive
“for me personally, Dynamine and Teacrine are not too bad, tho subtle. Sabroxy worked for a short while then seems to stop working.”Source discussion ↗
DynamineMostly positive
“If I pair it with something like Dynamine I get near all day energy. Not pushy or overly stimulating.”Source discussion ↗
DynamineMostly positive
“I've met more people who get nothing out of that than the contrary :(”Source discussion ↗
BaclofenMostly positive
“Baclofen(10/10): Not really a nootropic, but it felt identical to phenibut. Whats even better, I was able to take it regularly and keep the anxiety-reducing benefits...”Source discussion ↗
BaclofenMostly positive
“It works well. Currently taking 20mg/day, but will have to increase because I am not quite satisfied with the results. Having said that, I feel a little dizzy even on 20mg.”Source discussion ↗
BaclofenMostly positive
“The #1 tool in my arsenal. It helped me get out of my own thoughts and just live. I simply feel more alive, upbeat, enthusiastic, better mood, more outgoing/charming, more energy.”Source discussion ↗
BaclofenMostly positive
“Baclofen. I take 50 mg daily. Works great, almost no tolerance build up.”Source discussion ↗
L-PhenylalanineMixed
“I take 500mg L-Phenylalanine when I first get up in the morning and it appears to work well. I used to be terrible at getting out of bed in the morning, and have seen a great improvement over the last ~3 months.”Source discussion ↗
L-PhenylalanineMixed
“I'm not gonna take phenylalanine ever again. I've noticed so many bad symptoms because of it, i thought i just wasn't dosing it right.”Source discussion ↗
L-PhenylalanineMixed
“Now I take l-phenylalanine twice a day (500mg) for ADHD and feel great.”Source discussion ↗
L-PhenylalanineMixed
“I was using 1500mg L-phenylalanine daily with fantastic results for about two months”Source discussion ↗
LamotrigineMixed
“It helped me stay on Lamotrigine, which is the only med that works for my depression.”Source discussion ↗
LamotrigineMixed
“I’ve since trialled Pregabalin and currently been on Lamotrigine for 7 weeks and zero improvement.”Source discussion ↗
LamotrigineMixed
“I've realized I'm losing my short-term memory a lot as a side effect of Lamotrigine, 400 mg.”Source discussion ↗
LamotrigineMixed
“I was on Seroquel briefly, but found lamotrigine to be much more effective with less side effects.”Source discussion ↗
Weight LiftingMostly positive
“lift weights. Legs, chest, back, arms... It's a nice feeling when I stick some protein in the oven and can just pump out a few sets”Source discussion ↗