What people actually say

“I feel like I have all the positives of Adderall (focus, motivation, mood increase) without any noticeable downsides. No crash, no anxiety, no cardiac issues.”

“I woke up the next day feeling incredible! I felt light and buoyant...I felt light and buoyant. I had a strong desire to be outside in nature...my memory started to improve, my verbal fluency went up as well.”

“Within 3, 4 days I noticed a change. Since then, I still take Adderall and Vyvanse, with Memantine as a buffer.”

“Used memantine to get off of kratom and it worked amazingly! But now I’m dependent on memantine.”

“Sabroxy: Poor man's Ritalin, and cleaner feeling in my experience. Dopamine agonist. I take it once in a while if I need to be laser focused and awake.”

“I tested Sabroxy for quite some time now and found it very consistent in giving me brain fog and an overwhelmed feeling of demotivation.”

“Combined with caffeine and sabroxy, there was a notable improvement in my attention span and overall mood.”

“sabroxy is weaker but very pleasant and doesn't have any side effects I have noticed. Nice energy and mental focus boost.”

“The supplements that I have found to aid in improving my mood and anxiety the most are apigenin, saffron, and polygala.”

“I’ve found Polygala was much better for focus whereas agmatine was way better for my mood.”

“Polygala has multiple MOAs that pretty much lifts anxiety and my mood a bit.”

“polygala is fantastic... gives me a nice mood boost helps me focus... I have it and don't find much use for it in promoting focus or wakefulness.”

“I know pregnenalone helped me with that anxiety... 25mg a day is wonderful.”

“Now it's like 90% fixed by pregnenolone. However, I been taking around 10 to 20 mg this is the sweet spot for me if I take anymore I get the opposite reaction such as more fatigue and tiredness.”

“I've been taking pregnenolone, dhea, and tongkhat ali and it helps keep my mind straight while living alone, working alone.”

“I've never felt more comfortable in my own skin, more calm, or stable. Things just feel right. But: Definitely not a keeper for me. Either no effect or I get more jittery/anxious.”

“Huperzine a 250mcg a day fixed my dad right up. It's actually the same med and dosage used in China for dementia.”

“Huperzine-A - I initially took it for lucid dreaming, but it is a complete flop for me. Nothing changed. No vivid dreams, no brain function improvement. Nothing.”

“Huperzine A is absolutely magical for me... It increases REM phase of sleep => longer and more vivid dreams & feeling more recharged in the morning.”

“cats claw combined with bacopa and huperzine a. That stack really helped my verbal fluidity...”

“I was very anxious and listless for a while and the substances that helped me the most were Pramiracetam + alpha GPC.”

“I'm using the piracetam and pramiracetam combo because they help me feel more fluid.”

“Pramiracetam has always reliably worked for me. I find my recall is improved...but it made me too focused and had a blunting effect on my emotions.”

“I use it in the mornings instead of a large dose of Piracetam, and it helps with memory recall and the formation of new memories.”

“I take 200mcg eveyday, but for the first week I took 400mcg. It has exponentially helped my energy levels.”

“even the nootropics that some communities swear by did nothing for me (some that come to mind - racetams, tyrosine/NALT, NAC, methylated B vitamins...”

“200mcg of selenium everyday. Difference when I’m taking it and not taking it is absolutely astounding. Really improved thyroid numbers too.”

“I tried selenium for thyroid support but weirdly it ended up helping way more with energy and overall tiredness.”

“It makes me feel very relaxed, and if I take a strong dose I fall asleep within minutes, despite the fact that I normally get insomnia. It also fights anxiety effectively.”

“It did help me in the short term but, I don't think that targeting the gabaergic system is a good way to stop anxiety. Anything that targets this system will eventually cause rebound anxiety or dependency.”

“I drink gotu kola and vape cbd among other supplements and I think that's what helps with my ADHD the most - this combo gives me a stimulated feeling.”

“The gotu kola is similar. I take that before bed when I am on it as well. ... I experience a 'sleep like the dead for, say, 6 hours, then wake up and cannot go back to sleep' effect on Gotu Kola.”

“Metformin currently has enough data for me personally to feel comfortable not only taking it myself (and my wife), but also recommending it to my patients.”

“Berberine has done zero for my pre diabetic glucose levels or weight. Metformin has and I changed nothing else.”

“2 days with Metformin and that’s gone. I feel like I did when i was in my 30’s.”

“Metformin (2 months, hoping to reduce hunger or increase energy), and there is way many more and others I can't remember.”

“Other things are in that gray area like sulbutiamine, racetams, selegiline, and nicotine have helped me.”

“Before, I was trying some racetams but reading this article scared the hell out of me about racetams and I stopped.”

“even the nootropics that some communities swear by did nothing for me (some that come to mind - racetams, tyrosine/NALT, NAC, methylated B vitamins...”

“Noopept/racetams/choline useful to bring back my recall after I had destroyed it through years of dxm abuse. It DOES work for that, but if you are a healthy adult it does absolutely nothing.”