PlainPill

What people actually say

694 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
Blueberry ExtractMostly positive
“Organic blueberry supplements/or once a day blueberry juice may also help. I stress organic because I took sunkist blueberry supplements for a few months...big mistake, didn't feel well”
Source discussion ↗
4dmaMostly positive
“what really helped were a couple long courses of 4DMA. Daily first thing in the morning and I felt tremendous relief after a week or so, which was near-permanent.”
Source discussion ↗
4dmaMostly positive
“Then I tried 4-DMA, which is pretty good but not exactly for focus... it makes me feel quite weird, as in at the same time I get clarity of thought I also get almost paranoid”
Source discussion ↗
4dmaMostly positive
“4-DMA has been my go-to lately for all day focus and mental energy.”
Source discussion ↗
4dmaMostly positive
“4dma in my case gave me insomnia + anxiety.”
Source discussion ↗
TAK-653Mostly positive
“tak-653 has offered a noticable improvement to my ability to juggle concepts, retain them, and execute based off of what i learned.”
Source discussion ↗
TAK-653Mostly positive
“it has been shown to literally increase IQ as well, as well as working memory. in my experience, it is very potent at improving working memory”
Source discussion ↗
Lithium CarbonateMostly negative
“Took the life right out of me, made me feel like a zombie.”
Source discussion ↗
Lithium CarbonateMostly negative
“Lithium was horrible for me. The first few days I felt fine but after about a week I had an insane reaction to it... I actually felt like I had lost my sanity.”
Source discussion ↗
Lithium CarbonateMostly negative
“I was on lithium carbonate 1200mg... Had extremely low motivation, low mood and drive, did not find lots of pleasure in sex... Stopped all... Mood and libido returned maybe 80%”
Source discussion ↗
Lithium CarbonateMostly negative
“my experience of being put on lithium carbonate kind of ruined my opinion of lithium.”
Source discussion ↗
IbogaineMostly positive
“Ibogaine worked. I literally saw my brain heal. It's extremely unsafe to do it alone; a clinic is a must.”
Source discussion ↗
IbogaineMostly positive
“The only thing I know of that does what you’re looking for is ibogaine.”
Source discussion ↗
ButyrateNot enough data
“Butyrate is an HDAC inhibitor that is produced in our own bodies...increase gene transcription through being an HDAC inhibitor, as well as help with inflammation, mental health, cancer, blood sugar/insulin, mitochondria health, aging and more”
Source discussion ↗
SynapsaNot enough data
“Synapsa was def the best supplement I’ve taken when it comes to having control of my thoughts and cognition. But it negatively affected Libido tremendously.”
Source discussion ↗
SynapsaNot enough data
“The racetams are great. You have to figure out what works best for you. I take Synapsa.”
Source discussion ↗
SynapsaNot enough data
“I've used Synapsa for quite a while and I switched to Bacognize about two weeks ago. Due to much of the effect coming from physical change, it would still take time.”
Source discussion ↗
Na-Semax AmidateMostly positive
“The amount that it's increased my own creativity and comprehension of the world is astounding. I find myself able to vividly imagine things in my mind with a shocking amount of ease”
Source discussion ↗
Na-Semax AmidateMostly positive
“it pretty much guarantees a productive, happy day. Boosts in concentration, mood, wakefulness...only issue is that I have issues with insomnia”
Source discussion ↗
Na-Semax AmidateMostly positive
“There is an increased presence in the moment, helping to calm my anxiety. I use one pump in the morning. It potentiates caffeine, kratom, and Adderall”
Source discussion ↗
Na-Semax AmidateMostly positive
“The NA SEMAX Amidate I am using seems like it it beginning to repair my memory. My memory is ten times better... Social anxiety is %100 non-existent... sleep / wake pattern has improved vastly”
Source discussion ↗
ACD856Not enough data
“ACD really pulled me out of it last year. Then I noticed my habits improved: super focused going to gym again, quit nicotine pouches, mood drastically improved.”
Source discussion ↗
BacognizeMostly positive
“I noticed the effects after 2 weeks and ALCAR (500g) greatly accentuated those effects. Mostly the effects were very acute tunnel vision and focus.”
Source discussion ↗
BacognizeMostly positive
“Bacognize was one I took a long way back but I ended up with brain fog from it for some reason.”
Source discussion ↗
BacognizeMostly positive
“Basically anytime I cycled it I would get to a point after a couple weeks where I was noticeably more resistant to losing my composure in stressful situations.”
Source discussion ↗
BacognizeMostly positive
“Try Bacognize. Its the most non-drowsy bacopa I've tried and the only one I've had measurable memory improvements with (memorizing flash cards).”
Source discussion ↗
American GinsengMostly positive
“with my stack at the time which included American Ginseng I seemed to have an increased sense of will power/agency, decreased anxiety and increased sociability.”
Source discussion ↗
American GinsengMostly positive
“Ginseng does nothing for me, but as always, YMMV.”
Source discussion ↗
American GinsengMostly positive
“I did find panax and American ginseng both work similar to stimulants but aren't actually stimulants. Those are my caffeine replacements.”
Source discussion ↗
American GinsengMostly positive
“Drink american ginseng tea ... I'll definitely try out that ginseng tea. I've heard loads of good things about it, but never really looked into it.”
Source discussion ↗
Bacopa MonnieraMostly positive
“I would take Bacopa all the time...I had not so much success with it staying on it for more than a week.”
Source discussion ↗
“I would say one of the main things I experience with our Celastrus extract, is mental clarity. I noticed a sharp uptick in mental clarity. This is something I experience every time I take Celastrus.”
Source discussion ↗
“While all of these "worked", it was only when I took them and I ended up developing tolerances to all of them.”
Source discussion ↗
“Celastrus paniculatus, ginko biloba, gotu kola - this is my memory stack and its worked wonders”
Source discussion ↗
DHA Fish OilMostly positive
“Supplement wise I've found more motivation using Sulbutiamine, ALCAR, high DHA fish oil, and Black Seed Oil.”
Source discussion ↗
Uridine StackMostly positive
“Uridine stack helped me a lot on this matter. Tried so many things - but things improved drastically with this stack.”
Source discussion ↗
Uridine StackMostly positive
“explains why it works so well for my elderly parents”
Source discussion ↗
Uridine StackMostly positive
“I can personally recommend the basic Uridine Stack (sold on PowderCity)... which most beginners might want to go for.”
Source discussion ↗
Dual N-BackMostly positive
“I do believe that it can raise fluid intelligence, but I can't progress on dual n-back like a normal person could.”
Source discussion ↗
Dual N-BackMostly positive
“One thing I'd also suggest to maybe start now is Dual-N-Back exercise for 30mins every morning...sharp focus and working memory.”
Source discussion ↗
User reports — what people say about supplements — PlainPill