PlainPill

What people actually say

1,803 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
Choline CitrateMostly positive
“After taking Piracetam with Choline for a month, I can't say that I've ever noticed a distinct memory effect.”
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Choline CitrateMostly positive
“1:1 with citrate to be OK, 2:1 Piracetam:citrate works too but I get minor headaches sometimes.”
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Choline CitrateMostly positive
“I love choline, but I eat between 12-24 eggs a day and choline supplementation, to me, is useless”
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KetoMixed
“Keto cured me from sertraline and anxiety meds. When I am on it, I definitely feel the best mentally all around including focus.”
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KetoMixed
“I even did keto (keto increases dopamine) for a while and got the same results. Feeling great for a bit at the beginning, then shit, then great for 1-2 days after I quit.”
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KetoMixed
“Giving keto a shot could help you out with those crashes, reduce craving after you adjust, and give you more energy. I've noticed these things from my personal experience.”
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KetoMixed
“The effects you're describing sounds like Keto. Give it a try. Changed my life quite significantly.”
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DxmMixed
“taking 60mg of DXM per day off. I take 30mg and I still notice a helpful difference.”
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DxmMixed
“DXM did nothing to me except for nausea and ugly feeling to be honest.”
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DxmMixed
“It [DXM] works great for me at low levels. I usually take 60-120mg a few days a week and it yas been incredibly helpful for my depression and anxiety.”
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DxmMixed
“I had chronic mild serotonin syndrome from dxm... It’s been 4 years sober, it’s taken years to feel somewhat normal.”
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“When I take huperzine, one of the oxi/ani/pram and two tablespoons of MCT oil my brain and wakefulness feels better than having a cup of coffee.”
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“I've tried huperzine and polygala and those days in which I took both I felt even dumber.”
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“Huperzine and Vinpocetine I have tried only in combination, never exclusively, and have noticed subtle benefits.”
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“Each of these have definitely helped me with my anxiety and mood.”
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Vitamin BMostly negative
“Vitamin B which helps me feel alert, awake, energized, and gives me a little boost”
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Vitamin BMostly negative
“Vitamin B: Took it for years, made me feel calmer. Until it suddenly had the opposite effect.”
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Vitamin BMostly negative
“I take a lot of the things mentioned here and I've never noticed a change to ADHD: ... b vitamins (as separate things)”
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Vitamin BMostly negative
“I cannot take anything with vitamin B In it. Vitamin B makes my anxiety crazy, heart flutters.”
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PterostilbeneNot enough data
“two things that helped with my gray hair in my mid-60's has been pterostilbene and nicotinamide riboside.”
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PterostilbeneNot enough data
“I tried specially hard to stick with the latter but both just gave me panic attacks and it was horrible.”
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PterostilbeneNot enough data
“pterostilbene i thinks this is the one which does to trick for me. It also reduces anxiety but primarly is a strong antioxidant”
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PterostilbeneNot enough data
“I thought Pterostilbene (MAO-B inhibitor) was insane but this is another beast completely”
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“the best thing that has helped me with focus is definitely amphetamines.”
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“Even taking pause from amphetamines for over a year or more doesn't seem to reset it for me. It works great for maybe a month or two when I'm back on them, then it's all negative side effects.”
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“I've used amphetamines too, but I don't like how unclean it makes me feel.”
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“I feel good for about 40~ min and then I crash SO bad. I'm talking crippling anxiety”
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“Zero crash. Vasodilation instead of vasoconstriction with caffeine ... I can perform at a high level, heart rate and BP low, clear head, no headache”
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“even a theobromine supplement I tried...seem to make me more stressed out and anxious”
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“Personally I'd go for the theobromine which is the least aggressive of the 3. It's got a great mental effect and is found in chocolate.”
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“magnesium creatine and theobromine made for a perfect stack for me (who also have the same issues as you). this stack will help with restful sleep and with maintaining all day long wakefulness mental stamina. you can drink coffee while on this stack but do not add wellbutrin.”
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Mod-GrfMostly positive
“TB500 and Ipamorelin/mod-grf is what you want. It has helped me tremendously with my back issues.”
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Mod-GrfMostly positive
“i got no fat nor weight loss nor body transformation from taking Mod GFR and IPA... for now they are not worth it.”
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Mod-GrfMostly positive
“My friend has been on Ipamorelin / ModGRF since the second week of September and planning on cycling off in December. He is following the 3x a day routine with decent results.”
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Mod-GrfMostly positive
“I've been on ipa, mod grf for about 8 months...I'm also on TRT. 35 years old best shape of my life also look the best body wise and body fat%. As for my cognitive I am very sharp memories the best it's been in years.”
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“I have noticed over the last week specifically my mood is drastically better from when I started.”
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“the effect on my nervous system and mood has been extremely profound... i am also sleeping better.”
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“The focus, mood and energy boost is probably the best nootropic experience I have ever had.”
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“Mine was so high I needed to run caber, p5p didn't cut it.”
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“I added p5p and L-Dopa daily to combat that, as well as one dose of Caber 0.5mg weekly. Helped some but not much.”
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User reports — what people say about supplements — PlainPill