What people actually say
432 first-hand quotes, shortened but never edited — each links to the original discussion.
AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
GW-501516Mostly positive
“GW-501516 was a big one.”Source discussion ↗
GW-501516Mostly positive
“Look into these the cancer risk of gw 50156 comes from a poorly done study that gave rats 50 times the human dose per bodyweight”Source discussion ↗
GW-501516Mostly positive
“Cardarine 20mg, 10 mg Tadalafil, 50mg sildenafil, Shilajit, and fresh watermelon, beetroot, pomegranate juice.”Source discussion ↗
GW-501516Mostly positive
“For weight loss Cardarine is good. It tells your body to use fat as energy... my body fat has dropped abit but not loads but it's been 2 weeks.”Source discussion ↗
GW-501516Mostly positive
“cardarine is a beast when it comes to performance while training. Your endurance goes up the second day you're on it.”Source discussion ↗
SemaglutideMostly positive
“I've been inconstent with all 3, and I haven't seen much weight loss.”Source discussion ↗
SemaglutideMostly positive
“the only anti-aging drug I take is rapamycin and semaglutide, both of which blow metformin out of the water.”Source discussion ↗
SemaglutideMostly positive
“I see people losing weight on oprezic.”Source discussion ↗
SemaglutideMostly positive
“Semaglutide needs 30 mg capsules daily so that would be insane cost from American sources.”Source discussion ↗
SemaglutideMostly positive
“My wife has Sema,selenk, Semax”Source discussion ↗
BerberineMixed
“I also use Berberine to keep insulin low but it doesn't do a lot of the other stuff metformin does”Source discussion ↗
BerberineMixed
“I for now use berberine”Source discussion ↗
BerberineMixed
“I don't think berberine decreases testosterone?”Source discussion ↗
BerberineMixed
“I'm taking Berberine myself because I suspect the effects might be similar.”Source discussion ↗
BerberineMixed
“Berberine activates AMPK, like Metformin does”Source discussion ↗
Green TeaMostly positive
“I drink one cup of green tea per day now, down from 2-3 cups per day. I sleep better, I'm more emotionally stable”Source discussion ↗
Green TeaMostly positive
“I tend to do coffee in the morning and tea until 1-2pm without it affecting sleep that night.”Source discussion ↗
Green TeaMostly positive
“I recommend for reboosting just sip of green tea. Maybe 2 cups max.”Source discussion ↗
Green TeaMostly positive
“melatonin, krill oil complex, green tea extract”Source discussion ↗
Green TeaMostly positive
“Green tea extract can be bad for your liver, put me in hospital for a week with acute non-viral hepatitis.”Source discussion ↗
Intermittent FastingMostly positive
“8. Intermittent fasting”Source discussion ↗
Intermittent FastingMostly positive
“I fast for at least 16 hours, most days it ends up being around 20.”Source discussion ↗
Intermittent FastingMostly positive
“I would suggest trying Intermittent fasting. I have much better focus and clarity.”Source discussion ↗
Intermittent FastingMostly positive
“To avoid any loose skin, my working strategy has been: intermittent fasting religiously”Source discussion ↗
Intermittent FastingMostly positive
“I also did intermittent fasting for the first 4 months and lost my first 50 lbs that way.”Source discussion ↗
TesamorelinMixed
“Tesamorelin is good for visceral fat: https://pubmed.ncbi.nlm.nih.gov/25038357/”Source discussion ↗
TesamorelinMixed
“Any low blood sugar with mot or tesa?”Source discussion ↗
TesamorelinMixed
“Unless it’s ozempic, monjouro, tesamorelin, or rHGH he isnt... they’re all coming out of China.”Source discussion ↗
TesamorelinMixed
“Tesamorelin (which also really increased deep sleep metrics!!)”Source discussion ↗
TesamorelinMixed
“I am doing Tesa/Ipa 2mg/1mg 5on/2off AM fasted.”Source discussion ↗
CistancheMostly positive
“TONS of herbs/supplements (ginseng, cistanche, epimedium, shilajit, ashwagandha, he shou wu, zinc, magnesium, omega 3s, creatine, etc) all improve cognition and libido.”Source discussion ↗
CistancheMostly positive
“Testosterone boosting supplements (particulary Maca, Cistanche, Shilajit and Tongkat ali)”Source discussion ↗
CistancheMostly positive
“anything that will lower stress and throw in some Tongkat Ali, Boron, Cistanche and Shilajit (no other sups will help at all likely)”Source discussion ↗
CistancheMostly positive
“I think other dopaminergic compounds like Shilajit and Cistanche potentiate it”Source discussion ↗
CistancheMostly positive
“sabroxy skull Cap extract and cistanche is a powerful stack”Source discussion ↗
CJC-1295Mostly positive
“Combined with a GH releaser like mk677 or ipamorelin and cjc 1295”Source discussion ↗
CJC-1295Mostly positive
“I've found that growth hormone releasing hormone (GHRH), in the form of mod grf 1-29, really dose the trick for me”Source discussion ↗
CJC-1295Mostly positive
“give mod grf or cjc-1295 a try. Much healthier then stuff like quetiapine, trazadone, mirtazapine, etc ...”Source discussion ↗
CJC-1295Mostly positive
“CJC nodac /Ipa 500mcg/500mcg PM fasted before bed. 5on2off.”Source discussion ↗
CJC-1295Mostly positive
“Reconstituted a 5mg CJC-1295 (no DAC) vial...Next day: granular, sand-like sediment at the bottom”Source discussion ↗