PlainPill

What people actually say

432 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
TirzepatideMostly positive
“mounjaro has been the best. I lost like 15 pounds in two months on this thing.”
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TirzepatideMostly positive
“Semaglutide/tirzepatide”
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TirzepatideMostly positive
“I’m currently on tirzepatide 7.5mg (midway dose). Stacking sema because tirz isn’t helping it’s serious insomnia and sexual side effects.”
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TirzepatideMostly positive
“The amount of 40+ year old fitness frauds using tirzepatide to get lean is increasing dramatically”
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TirzepatideMostly positive
“we have plenty of Tirz for no reason but it was a good price”
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IpamorelinMostly positive
“I'm running ipam/mod/bpc/tb500 for a very complicated shoulder surgery”
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IpamorelinMostly positive
“I saw someone suggest bpc-157 and ipamorelin is good too”
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IpamorelinMostly positive
“Combined with a GH releaser like mk677 or ipamorelin and cjc 1295”
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IpamorelinMostly positive
“I have 3 ipa’s every day. Why don’t I look like this?”
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IpamorelinMostly positive
“Before bed Selank Dsip GHK-Cu Tesamorelin Ipamorelin”
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ProbioticsMostly positive
“I take red yeast rice, coq10, vitamin d, vitamin c, a probiotic and a multivitamin.”
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ProbioticsMostly positive
“Probiotics. To get good bacterias to my gut so it can produce more serotonin.”
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ProbioticsMostly positive
“Now I'm experimenting with many types of probiotics that increase serotonin. For me, it's as effective at improving my mood, but doesn't have any of the emotion-blunting effects.”
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ProbioticsMostly positive
“Nine years of antibiotic, creams, numerous treatments, even heavy duty accutane and still no solution to horrible acne. It took probiotics 9 days to solve everything!”
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ProbioticsMostly positive
“Probiotics”
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CordycepsMostly positive
“I have not taken anything that has come close to the endurance and oxygen intake increase I have from Cordyceps.”
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CordycepsMostly positive
“2 Capsules MycoBoost (Cordyceps + Yerba Mate) from Natural Stacks”
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CordycepsMostly positive
“Cordyceps worked pretty well imhe”
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CordycepsMostly positive
“Hypoglycemic: helps with insulin resistance. Otherwise useless.”
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CordycepsMostly positive
“Perhaps cordecyps as well since it's an adenosine agonist.”
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VyvanseMixed
“I tried Vyvanse, modafinil, ritalin, adderall for concetration and attention... in terms of ROI they don't deliver and I'm better of without them”
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VyvanseMixed
“ADHD Medication (specifically Adderall/Vyvanse) impact on health and longevity”
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VyvanseMixed
“amphetamines like Adderall and Vyvanse makes all the difference in my motivation and general functioning”
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VyvanseMixed
“check out Vyvanse or ask your Dr. about something similar.”
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VyvanseMixed
“I am more motivated, more capable of completing work, and feel 'cognitively enhanced' while I'm taking vyvanse”
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“I use nicotine occasionally. It’s great in small doses. Gum is best. Vape pens risk heavy metals or propylene glycol.”
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“If you consider nicotine, do so with gum of 2mg. I personally use it for exams and tests at school, because of the need of being cycled.”
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“I read a study recently that nicotine alone was not enough to improve memory.”
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“A good dose can be a cognitive enhancer though... Be careful not to take too much or it, at least for me, severely impedes thinking.”
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“Nicotine helps if you use it sparingly enough to not get addicted.”
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SaffronMostly positive
“After two weeks of taking I started feeling amazing, the depression was almost no existent anymore. But now its back again.”
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SaffronMostly positive
“Saffron was recommended to me aswell”
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SaffronMostly positive
“I've tried pelvic floor therapy, maca root, ashwagandha (had huge crash on that so be careful) ginkgo biloba, and saffron.”
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SaffronMostly positive
“Personally if i had SSRI induced sexual dysfunction, i would try saffron extract first.”
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SaffronMostly positive
“After saffron ingestion, my mind became clear again.”
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NMNMostly positive
“It seems like NAD gets you back to youthful levels of health, but isn’t going to supercharge anyone who is still there.”
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NMNMostly positive
“Podcast Notes/Ful Summary - David Sinclair, Ph.D. on NMN, Resveratrol, and Longevity”
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NMNMostly positive
“NMN and resveratrol”
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NMNMostly positive
“Anyone pairing Resveratrol with NMN or CoQ10 for anti-aging effects?”
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NMNMostly positive
“NAD+ you're better off buying NMN and TMG oral supps. NMN will convert to NAD+ and TMG will replace the methyl groups”
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User reports — what people say about supplements — PlainPill