Enclomiphene vs Zinc for hormones
Short answer: For hormones, users rate them about the same: 88% report improvement with Enclomiphene (96 reports) and 89% with Zinc (63 reports).
Enclomiphene has 2 meta-analyses and 3 randomized trials on PubMed; Zinc has 220 and 555.
Based on 373 reports about Enclomiphene and 1,264 about Zinc. Not medical advice.
| Enclomiphene Medication | Zinc Supplement | |
|---|---|---|
| User score | 45 | 42 |
| Verdict | Mostly positive | Mostly positive |
| Positive of reports that state an outcome | 61% | 61% |
| Reports | 373 | 1,264 |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 2 / 3 | 220 / 555 |
| Mainly used for | ||
| Weight loss % reporting improvement | — | 100% (3) |
| Appetite % reporting improvement | — | 33% (3) |
| Focus % reporting improvement | 50% (2) | 62% (26) |
| Energy % reporting improvement | 70% (10) | 71% (51) |
| Sleep % reporting improvement | 75% (4) | 82% (68) |
| Anxiety % reporting improvement | 0% (2) | 73% (30) |
| Mood % reporting improvement | 65% (17) | 80% (61) |
| Memory % reporting improvement | — | 20% (5) |
| Performance % reporting improvement | 33% (3) | 90% (20) |
| Recovery % reporting improvement | 100% (2) | 86% (7) |
| Pain & inflammation % reporting improvement | — | 56% (9) |
| Digestion % reporting improvement | — | 0% (2) |
| Libido % reporting improvement | 71% (24) | 88% (95) |
| Hormones % reporting improvement | 88% (96) | 89% (63) |
| Heart & lipids % reporting improvement | — | 50% (2) |
| Skin & hair % reporting improvement | — | 81% (32) |
| Immunity % reporting improvement | — | 86% (28) |
| Common side effects | eye floaters, blurry vision, mood swings, fatigue | nausea, fatigue, stomach issues, copper depletion |
| Typical dose reported | 12.5 g daily (comment; likely mg) / daily for 2 months (comment) | daily |
SERM therapy is associated with significantly improved levels of TT, LH, and FSH in hypogonadal men compared to placebo, and significantly enhanced levels of LH and FSH compared to T gel. The findings suggest that SERM therapy effectively increases TT levels in men with functional hypogonadism and should be considered as an alternative to T gel therapy.
Arch Endocrinol Metab, 2025 ↗“I second Enclomiphene citrate. Been on 12.5mg per day sublingual pill and my test went from 430 to 950. No side effects other than being more horny.”
Acne patients have decreased serum zinc levels. Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment.
Dermatol Ther, 2020 ↗“I had actual energy in the mornings for the first time I could remember.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate