PlainPill

Zinc vs Zinc Picolinate for immunity

Short answer: For immunity, more users report improvement with Zinc Picolinate — 100% of 8 reports, versus 89% of 37 for Zinc.

Zinc has 220 meta-analyses and 555 randomized trials on PubMed; Zinc Picolinate has 220 and 555.

Based on 1,594 reports about Zinc and 95 about Zinc Picolinate. Not medical advice.

Zinc
Supplement
Zinc Picolinate
Supplement
Users say it helped59%helped510 reports · high confidence69%helped34 reports · medium confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs220 / 555220 / 555
Mainly used for
Libido
% reporting improvement
90% (120)100% (7)
Hormones
% reporting improvement
88% (94)—
Sleep
% reporting improvement
84% (76)75% (4)
Mood
% reporting improvement
81% (68)100% (5)
Energy
% reporting improvement
74% (57)60% (5)
Common side effectsnausea, stomach issues, vomiting, copper deficiencystomach issues, nausea, brain fog, insomnia
Typical dose reported75 mg30 mg / before bed
Zinc
Latest review conclusion

Acne patients have decreased serum zinc levels. Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment.

Dermatol Ther, 2020 ↗
What a user said
“I had actual energy in the mornings for the first time I could remember.”
Full Zinc profile →
Zinc Picolinate
Latest review conclusion

Acne patients have decreased serum zinc levels. Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment.

Dermatol Ther, 2020 ↗
What a user said
“After 15 mins or so, I experienced these effects: Warm body temperature, Heightened self-esteem, Dulling of emotions... Only bad thing is I feel slightly dumber.”
Full Zinc Picolinate profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate