People mainly take Dim for mood, hormones. Based on 33 first-hand reports and 111 meta-analyses & systematic reviews in the medical literature. Ranked #509 of 1,974 overall.
Of reports that state an outcome, 67% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Results of this systematic review and meta-analysis reveal that BLT was an effective adjunctive treatment for nonseasonal depressive disorders. Additionally, results suggest that BLT may improve the response time to the initial treatment.
PubMed 39356500 ↗Conclusion: Conclusions: DIM may be reversible with management that can include drug discontinuation, dose adjustment, and the prescription of a medication used to treat idiopathic myoclonus. Based on the main clinical constellation of symptoms and pathophysiological mechanisms found in this study, DIM can be categorized into three types: type 1 (serotonin syndrome), type 2 (non-serotonin syndrome), and type 3 (unknown).
PubMed 39859113 ↗Conclusion: Hysteroscopic diagnostic criteria are highly accurate and sensitive for detecting chronic endometritis. Absence of hysteroscopic suspicion might be sufficient to exclude disease. However, in cases in which hysteroscopic diagnostic findings of chronic endometritis are present, performing endometrial biopsy is recommended to confirm the diagnosis due to risk of false positives with hysteroscopy alone.
PubMed 40073921 ↗Conclusion: Out of the 24 publications focusing on sleep, there was substantial evidence for blue-blocking glasses being a successful intervention for reducing sleep onset latency in patients with sleep disorders, jet lag, or variable shift work schedules. Given the well-established biological mechanism and clinical research showing that blue-blocking glasses are effective for inducing sleep, they are a viable intervention to recommend to patients with insomnia or a delayed sleep phase.
PubMed 34030534 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“Don't take DIM your testosterone levels will probably increase as there is no aromatization of testosterone but having low estrogen is just as bad”
“which is why stacking it with DIM is not a bad idea as it acts to limit aromatization”
“supplement with DIM for excess estrogen”
“DIM does not seem to do anything for me.”
“I would recommend throwing in some DIM & calcium- deglucarate along with boron & chromium if high estrogen is the problem”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate