What are the side effects of Dim?

Users most often report low estrogen, joint damage, anti-androgen effects, breast tenderness, sadness. Side effects came up 6 times across 94 reports.

User reports can't establish safety. PubMed lists 111 meta-analyses and 297 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Dim side effects

Across 94 first-hand reports, people mentioned a side effect 6 times (about 6 per 100 reports). The most common: low estrogen, joint damage, anti-androgen effects. User reports show what people notice — they can't tell you whether Dim is safe for you.

Reported side effects

low estrogen2

joint damage1

anti-androgen effects1

breast tenderness1

sadness1

In their own words

“I'm taking dim! Gonna take a break bc I feel like my progesterone is getting too high (I get very tender b**bs and kinda sad but libido is back which is awesome)”

MixedRead the discussion ↗

“DIM does not seem to do anything for me.”

Didn't helpRead the discussion ↗

“Tried it brother, that litterly tanked my estrogen.”

MixedRead the discussion ↗

Is Dim safe? What the research covers

AResearch: Strong111 meta-analyses · 297 randomized trials on PubMed

Am J Obstet Gynecol · 2025

Hysteroscopic criteria for the diagnosis of chronic endometritis: a systematic review and diagnostic test accuracy meta-analysis

Conclusion: Hysteroscopic diagnostic criteria are highly accurate and sensitive for detecting chronic endometritis. Absence of hysteroscopic suspicion might be sufficient to exclude disease. However, in cases in which hysteroscopic diagnostic findings of chronic endometritis are present, performing endometrial biopsy is recommended to confirm the diagnosis due to risk of false positives with hysteroscopy alone.