PlainPill

Nolvadex vs Vitamin D for hormones

Short answer: For hormones, more users report improvement with Nolvadex — 97% of 37 reports, versus 91% of 75 for Vitamin D.

Nolvadex has 6 meta-analyses and 22 randomized trials on PubMed; Vitamin D has 3,251 and 4,560.

Based on 219 reports about Nolvadex and 3,040 about Vitamin D. Not medical advice.

Nolvadex
Medication
Vitamin D
Supplement
User score4546
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
67%67%
Reports2193,040
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs6 / 223,251 / 4,560
Mainly used for
Weight loss
% reporting improvement
—70% (10)
Appetite
% reporting improvement
—67% (3)
Focus
% reporting improvement
—83% (59)
Energy
% reporting improvement
100% (3)87% (252)
Sleep
% reporting improvement
—52% (119)
Anxiety
% reporting improvement
—64% (90)
Mood
% reporting improvement
—88% (390)
Memory
% reporting improvement
—87% (15)
Performance
% reporting improvement
50% (2)100% (27)
Recovery
% reporting improvement
—92% (13)
Pain & inflammation
% reporting improvement
—74% (31)
Digestion
% reporting improvement
—50% (14)
Libido
% reporting improvement
67% (3)82% (51)
Hormones
% reporting improvement
97% (37)91% (75)
Blood sugar
% reporting improvement
—100% (3)
Heart & lipids
% reporting improvement
—65% (17)
Skin & hair
% reporting improvement
—87% (31)
Immunity
% reporting improvement
—98% (93)
Longevity
% reporting improvement
—86% (14)
Common side effectsfatigue, depression, mood swings, brain foginsomnia, anxiety, fatigue, hypercalcemia
Typical dose reported3 weeks at 10 mg dailydaily
Nolvadex
Latest review conclusion

The current debate is centered on whether the optimal strategy is to give an aromatase inhibitor initially or after several years of tamoxifen treatment. Multiple important questions remain, including the predictive value of molecular markers such as progesterone receptor, the optimal duration of aromatase inhibitor therapy, the long-term adverse effects, and the relative efficacy and toxicity of the different aromatase inhibitors.

Clin Cancer Res, 2006 ↗
What a user said
“This is now 2nd day on nolva and I swaer my balls are about back to normal. Energy is a bit better”
Full Nolvadex profile →
Vitamin D
Latest review conclusion

These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.

Obes Rev, 2015 ↗
What a user said
“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
Full Vitamin D profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate