PlainPill

Nolvadex vs Testosterone for hormones

Short answer: For hormones, more users report improvement with Nolvadex — 97% of 37 reports, versus 91% of 101 for Testosterone.

Nolvadex has 6 meta-analyses and 22 randomized trials on PubMed; Testosterone has 75 and 125.

Based on 219 reports about Nolvadex and 922 about Testosterone. Not medical advice.

Nolvadex
Medication
Testosterone
Medication
User score4553
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
67%78%
Reports219922
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs6 / 2275 / 125
Mainly used for
Weight loss
% reporting improvement
—94% (47)
Focus
% reporting improvement
—83% (30)
Energy
% reporting improvement
100% (3)93% (88)
Sleep
% reporting improvement
—79% (19)
Anxiety
% reporting improvement
—80% (25)
Mood
% reporting improvement
—89% (117)
Memory
% reporting improvement
—100% (2)
Performance
% reporting improvement
50% (2)98% (179)
Recovery
% reporting improvement
—92% (26)
Pain & inflammation
% reporting improvement
—71% (7)
Libido
% reporting improvement
67% (3)90% (78)
Hormones
% reporting improvement
97% (37)91% (101)
Heart & lipids
% reporting improvement
—56% (9)
Skin & hair
% reporting improvement
—40% (5)
Longevity
% reporting improvement
—67% (3)
Common side effectsfatigue, depression, mood swings, brain fogsuppression, hair loss, acne, water retention
Typical dose reported3 weeks at 10 mg daily200 mg / weekly
Nolvadex
Latest review conclusion

The current debate is centered on whether the optimal strategy is to give an aromatase inhibitor initially or after several years of tamoxifen treatment. Multiple important questions remain, including the predictive value of molecular markers such as progesterone receptor, the optimal duration of aromatase inhibitor therapy, the long-term adverse effects, and the relative efficacy and toxicity of the different aromatase inhibitors.

Clin Cancer Res, 2006 ↗
What a user said
“This is now 2nd day on nolva and I swaer my balls are about back to normal. Energy is a bit better”
Full Nolvadex profile →
Testosterone
Latest review conclusion

The guidelines also provide recommendations regarding identification of patients, dosing, monitoring, and follow-up. This Practice Pearl will discuss evidence-based testosterone therapy for management of HSDD in postmenopausal women.

Menopause, 2023 ↗
What a user said
“Feel the best I've ever felt in my life. TRT and peptides have been game changers for me!”
Full Testosterone profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate