PlainPill

Melanotan 1 vs Melanotan Ii for skin & hair

Short answer: For skin & hair, more users report improvement with Melanotan 1 — 100% of 5 reports, versus 91% of 67 for Melanotan Ii.

Melanotan 1 has 0 meta-analyses and 1 randomized trials on PubMed; Melanotan Ii has 1 and 1.

Based on 21 reports about Melanotan 1 and 145 about Melanotan Ii. Not medical advice.

Melanotan 1
Peptide
Melanotan Ii
Peptide
User score3761
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
66%63%
Reports21145
ResearchCResearch: LimitedBResearch: Moderate
Meta-analyses / RCTs0 / 11 / 1
Mainly used for
Weight loss
% reporting improvement
—100% (11)
Appetite
% reporting improvement
—67% (6)
Sleep
% reporting improvement
—0% (4)
Mood
% reporting improvement
—40% (5)
Performance
% reporting improvement
—100% (5)
Libido
% reporting improvement
—96% (47)
Heart & lipids
% reporting improvement
—33% (3)
Skin & hair
% reporting improvement
100% (5)91% (67)
Immunity
% reporting improvement
—100% (2)
Common side effectsnausea, freckles, headrush, darkened molesnausea, flushing, freckles, darkened moles
Typical dose reportedNot listedNot listed
Melanotan 1
What a user said
“And the last one I attribute my results to is Melanotan1 due to the facial coloring which also accentuates structure and created contrast especially with my eyes.”
Full Melanotan 1 profile →
Melanotan Ii
Latest review conclusion

Almost all studies are in the preclinical phase. There are currently no effective clinical treatments for MC4R-deficient obese patients, although MC4R agonists are being developed and are entering phase I and II trials.

Int J Obes (Lond), 2014 ↗
What a user said
“I've found that getting sun within 3-12 hours will produce the desired result.”
Full Melanotan Ii profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate