PlainPill

Glycine vs Magnesium L-Threonate for sleep

Short answer: For sleep, users rate them about the same: 85% report improvement with Glycine (204 reports) and 84% with Magnesium L-Threonate (140 reports).

Glycine has 392 meta-analyses and 620 randomized trials on PubMed; Magnesium L-Threonate has 0 and 3.

Based on 562 reports about Glycine and 602 about Magnesium L-Threonate. Not medical advice.

Glycine
Supplement
Magnesium L-Threonate
Supplement
User score5256
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
71%73%
Reports562602
ResearchAResearch: StrongCResearch: Limited
Meta-analyses / RCTs392 / 6200 / 3
Mainly used for
Focus
% reporting improvement
67% (9)99% (73)
Energy
% reporting improvement
92% (13)86% (14)
Sleep
% reporting improvement
85% (204)84% (140)
Anxiety
% reporting improvement
77% (48)94% (66)
Mood
% reporting improvement
88% (24)89% (35)
Memory
% reporting improvement
67% (3)90% (29)
Performance
% reporting improvement
100% (3)100% (2)
Recovery
% reporting improvement
100% (7)100% (2)
Pain & inflammation
% reporting improvement
100% (3)75% (4)
Digestion
% reporting improvement
—33% (3)
Libido
% reporting improvement
50% (2)—
Skin & hair
% reporting improvement
100% (10)—
Longevity
% reporting improvement
100% (2)—
Common side effectsinsomnia, vivid dreams, anxiety, drowsinessvivid dreams, insomnia, headache, anxiety
Typical dose reported2 g / daily6 caps / daily
Glycine
Latest review conclusion

In studies using high-throughput metabolomics, several blood amino acids appear to be consistently associated with the risk of developing type 2 diabetes.

Diabetes Care, 2016 ↗
What a user said
“2 grams with 200mg magnesium before bed gives me crazy good sleep. Crazy vivid dreams.”
Full Glycine profile →
Magnesium L-Threonate
What a user said
“I just tried magnesium theronate the other day and I feel like a new person... My memory recall is better too. Emotions and anxiety have levelled DRASTICALLY.”
Full Magnesium L-Threonate profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate