Glycine vs Magnesium Glycinate for sleep
Short answer: For sleep, more users report improvement with Glycine — 85% of 204 reports, versus 80% of 527 for Magnesium Glycinate.
Glycine has 392 meta-analyses and 620 randomized trials on PubMed; Magnesium Glycinate has 0 and 4.
Based on 562 reports about Glycine and 1,323 about Magnesium Glycinate. Not medical advice.
| Glycine Supplement | Magnesium Glycinate Supplement | |
|---|---|---|
| User score | 52 | 60 |
| Verdict | Mostly positive | Mostly positive |
| Positive of reports that state an outcome | 71% | 67% |
| Reports | 562 | 1,323 |
| Research | AResearch: Strong | CResearch: Limited |
| Meta-analyses / RCTs | 392 / 620 | 0 / 4 |
| Mainly used for | ||
| Focus % reporting improvement | 67% (9) | 67% (48) |
| Energy % reporting improvement | 92% (13) | 63% (51) |
| Sleep % reporting improvement | 85% (204) | 80% (527) |
| Anxiety % reporting improvement | 77% (48) | 78% (255) |
| Mood % reporting improvement | 88% (24) | 70% (84) |
| Memory % reporting improvement | 67% (3) | 88% (8) |
| Performance % reporting improvement | 100% (3) | 89% (9) |
| Recovery % reporting improvement | 100% (7) | 100% (10) |
| Pain & inflammation % reporting improvement | 100% (3) | 91% (11) |
| Digestion % reporting improvement | — | 57% (14) |
| Libido % reporting improvement | 50% (2) | 53% (17) |
| Hormones % reporting improvement | — | 100% (5) |
| Heart & lipids % reporting improvement | — | 67% (6) |
| Skin & hair % reporting improvement | 100% (10) | 75% (4) |
| Longevity % reporting improvement | 100% (2) | — |
| Common side effects | insomnia, vivid dreams, anxiety, drowsiness | insomnia, anxiety, drowsiness, fatigue |
| Typical dose reported | 2 g / daily | at sleep time |
GlycineFull Glycine profile →
Latest review conclusion
In studies using high-throughput metabolomics, several blood amino acids appear to be consistently associated with the risk of developing type 2 diabetes.
Diabetes Care, 2016 ↗What a user said
“2 grams with 200mg magnesium before bed gives me crazy good sleep. Crazy vivid dreams.”
Magnesium GlycinateFull Magnesium Glycinate profile →
What a user said
“The brain fog started lifting. The constant low-grade anxiety that I had accepted as "normal" started to ease.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate