GHK-Cu vs Glutathione for skin & hair
Short answer: For skin & hair, users rate them about the same: 87% report improvement with GHK-Cu (202 reports) and 90% with Glutathione (10 reports).
GHK-Cu has 0 meta-analyses and 1 randomized trials on PubMed; Glutathione has 967 and 1,685.
Based on 496 reports about GHK-Cu and 156 about Glutathione. Not medical advice.
| GHK-Cu Peptide | Glutathione Supplement | |
|---|---|---|
| Users say it helped | 62%helped223 reports · high confidence | 71%helped37 reports · medium confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | CResearch: Limited | AResearch: Strong |
| Meta-analyses / RCTs | 0 / 1 | 967 / 1,685 |
| Mainly used for | ||
| Skin & hair % reporting improvement | 87% (202) | 90% (10) |
| Pain & inflammation % reporting improvement | 90% (31) | 100% (3) |
| Recovery % reporting improvement | 96% (27) | 100% (2) |
| Weight loss % reporting improvement | 88% (8) | — |
| Energy % reporting improvement | — | 100% (7) |
| Common side effects | injection site, redness, stinging, injection pain | injection site, insomnia, stomach issues, weakness |
| Typical dose reported | Not listed | 500 mg |
GHK-CuFull GHK-Cu profile →
What a user said
“Love it. 44 F. Totally helped even out my skin tone (Irish red cheeks), reduced wrinkles on my forehead and neck, thickened my hair which had been thinning, and grew my eye lashes.”
GlutathioneFull Glutathione profile →
Latest review conclusion
IV glutathione is contraindicated due to lack of efficacy and side effects. It may work more as an antioxidant in melasma.
Int J Dermatol, 2025 ↗What a user said
“IM 600mg 2x week. My head is clear, my energy is so much better and my skin is glowing!”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate