Enclomiphene vs Vitamin D for hormones
Short answer: For hormones, users rate them about the same: 88% report improvement with Enclomiphene (96 reports) and 87% with Vitamin D (55 reports).
Enclomiphene has 2 meta-analyses and 3 randomized trials on PubMed; Vitamin D has 3,251 and 4,560.
Based on 373 reports about Enclomiphene and 2,323 about Vitamin D. Not medical advice.
| Enclomiphene Medication | Vitamin D Supplement | |
|---|---|---|
| User score | 45 | 48 |
| Verdict | Mostly positive | Mostly positive |
| Positive of reports that state an outcome | 61% | 65% |
| Reports | 373 | 2,323 |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 2 / 3 | 3,251 / 4,560 |
| Mainly used for | ||
| Weight loss % reporting improvement | — | 62% (8) |
| Appetite % reporting improvement | — | 67% (3) |
| Focus % reporting improvement | 50% (2) | 82% (55) |
| Energy % reporting improvement | 70% (10) | 87% (215) |
| Sleep % reporting improvement | 75% (4) | 50% (105) |
| Anxiety % reporting improvement | 0% (2) | 65% (82) |
| Mood % reporting improvement | 65% (17) | 88% (308) |
| Memory % reporting improvement | — | 83% (12) |
| Performance % reporting improvement | 33% (3) | 100% (23) |
| Recovery % reporting improvement | 100% (2) | 91% (11) |
| Pain & inflammation % reporting improvement | — | 73% (30) |
| Digestion % reporting improvement | — | 50% (14) |
| Libido % reporting improvement | 71% (24) | 80% (45) |
| Hormones % reporting improvement | 88% (96) | 87% (55) |
| Blood sugar % reporting improvement | — | 100% (2) |
| Heart & lipids % reporting improvement | — | 60% (15) |
| Skin & hair % reporting improvement | — | 89% (28) |
| Immunity % reporting improvement | — | 99% (74) |
| Longevity % reporting improvement | — | 78% (9) |
| Common side effects | eye floaters, blurry vision, mood swings, fatigue | insomnia, anxiety, fatigue, hypercalcemia |
| Typical dose reported | 12.5 g daily (comment; likely mg) / daily for 2 months (comment) | daily |
SERM therapy is associated with significantly improved levels of TT, LH, and FSH in hypogonadal men compared to placebo, and significantly enhanced levels of LH and FSH compared to T gel. The findings suggest that SERM therapy effectively increases TT levels in men with functional hypogonadism and should be considered as an alternative to T gel therapy.
Arch Endocrinol Metab, 2025 ↗“I second Enclomiphene citrate. Been on 12.5mg per day sublingual pill and my test went from 430 to 950. No side effects other than being more horny.”
These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.
Obes Rev, 2015 ↗“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate