PlainPill

What people actually say

6,163 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
L-DopaMixed
“I'm getting tyrosine, Alpha GPC, even l dopa. Doesn't do anything until some dopamine release happens.”
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L-DopaMixed
“I've taken 5-HTP, L-Dopa, L-Theanine, and L-Tyrosine. None of them have done anything for me over a span of weeks”
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L-DopaMixed
“I took P5P, zinc, L-dipa, tyrosine and ext supplements you guys recommended”
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L-DopaMixed
“ive tried 98% l-dopa and hated it, crashed hard after 40 minutes to 1h”
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L-DopaMixed
“I would be particularly careful with both the Mucuna pruriens, L-DOPA, and Rhodiola”
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L-DopaMixed
“I don't think L-Dopa is going to help you at all.”
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L-DopaMixed
“I took some L-Dopa and triggered a nasty reaction”
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SarcosineMostly positive
“sarcosine + NAC nailed it. I literally cannot tell the difference. I feel so amazing.”
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SarcosineMostly positive
“long courses of Sarcosine (daily for a month+ at a time) helped tremendously and permanently, however when I tried it again more recently it triggered anxiety and overthinking.”
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SarcosineMostly positive
“GlyT1 Inhibitors: Sarcosine and (lesser extent) dimethylglycine cause glycine reuptake inhibition, proven quite effective for anxiety ... Helps me a lot.”
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SarcosineMostly positive
“2000mg sarcosine helps with the emotional blunting often seen in schizophrenia, and it aids cognitive performance through enhanced NMDA signaling. I have taken both for a few weeks and they have helped me tremendously.”
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SarcosineMostly positive
“500mg sarcosine mid day every other day and I'm getting so much better.”
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SarcosineMostly positive
“Sarcosine has been the only supplement that made significant changes when it came to depression and parts of my anxiety.”
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SarcosineMostly positive
“One thing I add to NAC dose (2g or so) is also 2g of Sarcosine (methyl-glycine). This was in a supplement called profrontal. Can add in alpha Lipoic acid as an enhancer. This helps me a ton with anhedonia!”
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SarcosineMostly positive
“just 1 dose of sarcosine had me feeling incredible. It felt as though I could breathe again. Anxiety lifted, mood was relaxed but NOT tired”
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SarcosineMostly positive
“Nothings worked except Sarcosine which has helped me very subtly.”
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SarcosineMostly positive
“I've had considerable result with this stack, though, a bit inconsistent.”
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SarcosineMostly positive
“Sarcosine has been phenomenal for my social anxiety lately.”
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SarcosineMostly positive
“I combine it with N-Acetyl-Cystine and helps me with mood and anhedonia. I'm not sure about it's effects on sleep quality.”
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SarcosineMostly positive
“I got those symptoms after taking shit tons of it for a while... I think sarcosine and glycine help me reverse it... I remember being super anhedonic... Now I'm back to feeling caffeine pretty much as normal again. Sarcosine and glycine seemed to give me that energy and emotion back.”
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SarcosineMostly positive
“Sarcosine, a schizophrenic supplement treatment, has successfully treated my Dissociative Identity Disorder and about a whopping 43-68% of my crippling DPDR/dissociation/brain fog; am taking 500mg twice a day.”
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SarcosineMostly positive
“I've only been on Sarcosine (1 gram three times a day) for almost a week now, but it seems to have completely obliterated my old, self-destructively negative thinking patterns”
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SarcosineMostly positive
“I've since made the switch to ND's lemon balm tablets/sarcosine as well as gingko, 5-htp... been positive”
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Resistance TrainingMostly positive
“more weight training. I was pumping iron, but not often enough so I lost more muscle mass than what I needed to.”
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Resistance TrainingMostly positive
“I find resistance training especially effective. Quads, glutei, calves, triceps, biceps, shoulders, abs - get them all reasonable sore, and you crash like a baby.”
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Resistance TrainingMostly positive
“Last year I stopped wasting my time with videos games and started hitting the weights. Changed my life.”
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Resistance TrainingMostly positive
“I made incredible strides and even worked through the right shoulder issue that had been hampering me for years.”
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Resistance TrainingMostly positive
“my hack to get it up without pharmaceuticals and have increased libido. Is doing lots of squats with weights”
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Resistance TrainingMostly positive
“Around month 2 I also started resistance training because I know it's especially important with PMOS...I've just slowly increased my dose whenever I felt like it was needed”
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Resistance TrainingMostly positive
“Brilliant focus in the gym too - for me having a decent routine at the gym also helps with my mood and adhd”
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Resistance TrainingMostly positive
“Now I do 3 lifting days (upper, lower, full-body split). Big change here was actually lifting to failure.”
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Resistance TrainingMostly positive
“I've been able to lift higher weights than when I started (20% on average)”
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Resistance TrainingMostly positive
“I focused on strength and muscle (re)gain with 3 - 4 times a week full body weight lifting, and 2 - 3 times 60 minute zone 2 incline WALKING.”
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Resistance TrainingMostly positive
“Resistance training and sex are the only ones off hand that I can remember for certain.”
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Resistance TrainingMostly positive
“I've built lots of muscle - definitely no body builder but I'm happy with the amount of lean muscle I've been able to build”
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Resistance TrainingMostly positive
“Still working out at least 4 days a week and hitting my 10k steps everyday”
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Resistance TrainingMostly positive
“I train at the gym three times per week, mostly focusing on compound movements with moderate weights.”
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Resistance TrainingMostly positive
“I started going to the gym 5-7 days a week”
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DihexaMostly positive
“The effects have been promising, because I found myself not only better in actual routine work, but also studying and learning, which was really hard to me before. It felt like combining mental clarity with neural plasticity.”
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DihexaMostly positive
“I've taken it three times, all orally. It's easily the most profound substance i've tried yet...Better memory and general retention, greater plasticity...improved physical performance”
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