What people actually say
5,470 first-hand quotes, shortened but never edited — each links to the original discussion.
AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
MemantineMixed
“I noticed benefits as early as 3 days of taking 10mgs daily in dived doses.”Source discussion ↗
MemantineMixed
“The best thing that helps me is venlafaxine and memantine, but I'm currently taking a tolerance break from memantine.”Source discussion ↗
MemantineMixed
“Used memantine to get off of kratom and it worked amazingly! But now I’m dependent on memantine.”Source discussion ↗
MemantineMixed
“I really like Memantine and Agmatine. Both works effective in terms of treating my anxiety and anhedonia. Unfortunately they both create too many side-effects. Memantine makes euphoric and wierd.”Source discussion ↗
MemantineMixed
“I've been testing memantine at 5 mgs for about a week. It's been pretty great so far. Calm focus, increased sex drive, a little detached.”Source discussion ↗
MemantineMixed
“Chronically, it seems to have caused somewhat of an improvement in my symptoms and is probably the most effective thing I've tried on this list, but I'm definitely still depressed.”Source discussion ↗
MemantineMixed
“It ruined me. My thoughts are lost i can't get my words out. I feel like an idiot. It's been over 6 months since I've stopped.”Source discussion ↗
MemantineMixed
“Within 3, 4 days I noticed a change. Since then, I still take Adderall and Vyvanse, with Memantine as a buffer.”Source discussion ↗
NiacinMostly positive
“If you over methylate, niacin may also help you. Binds to free methyl groups... It's how I fixed my heart palpitations after taking methylsulfonymethan.”Source discussion ↗
NiacinMostly positive
“Been taking Niacin, but other than the flush, I've found it makes me feel kinda irritable after taking it and my stomach doesn't feel great.”Source discussion ↗
NiacinMostly positive
“I take niacin daily and have noticed big improvements in mental clarity / focus.”Source discussion ↗
NiacinMostly positive
“it takes close to 10 grams of niacin a day to tame my symptoms and have me feeling good.”Source discussion ↗
NiacinMostly positive
“I've been megadosing Niacin for a couple of years and anecdotally feel like it's improving my health.”Source discussion ↗
NiacinMostly positive
“Niacin (as nicotinic acid, no relation to nicotine) can also help with NAD (worked for me).”Source discussion ↗
NiacinMostly positive
“Had bad flushing w/ the niacin. Felt like I was on fire, massive blotching covered entire body.”Source discussion ↗
NiacinMostly positive
“I cured it with micro dosing mushrooms, niacin and lions mane (took about 6 months, with 4 days on, 3 days off).”Source discussion ↗
NiacinMostly positive
“Ever since I started taking niacin daily it's greatly reduced the frequency and intensity of them, but you have to get the flushing kind.”Source discussion ↗
NiacinMostly positive
“I've experienced a big improvement in this after taking B3 (in the form of nicotinic acid).”Source discussion ↗
NiacinMostly positive
“I take nicotine and the B3 niacin. I think it helps with anxiety. 100mg dose.”Source discussion ↗
NiacinMostly positive
“I saw a notable difference after a month of 250mg/day...I got sick of cutting the caplets, so I've been taking 500mg for the last 2 months.”Source discussion ↗
NiacinMostly positive
“I have suffered from fatigue for decades, but thanks to it I feel better than ever, I take 500-1000 mg/day.”Source discussion ↗
NiacinMostly positive
“I have been using niacin (1 gram/3 times a day) for about a month and I do notice an increase in energy when I take it.”Source discussion ↗
NiacinMostly positive
“High doses of niacin improves blood flow and hormone production. I noticed a difference before even looking into it... I had a lower sex drive that’s been awakened by niacin”Source discussion ↗
NiacinMostly positive
“I've also been doing a Niacin flush 1000mg, the sauna and exercising daily and plan on continuing because it has also been helping”Source discussion ↗
EphedrineMixed
“I was a heavy 1,3 dimeth (germanium), caffeine, and sometimes ephedrine addict and now, I don't feel the need to take any of it.”Source discussion ↗
EphedrineMixed
“This morning I had about 200mg of caffeine with ephedrine pre-workout because I didnt get the best sleep last night. I could not focus at ALL today at work.”Source discussion ↗
EphedrineMixed
“Ephedrine gives me tons of energy, makes me happy, positive, and talkative. It's an excellent pre-workout, though it doesn't suppress my appetite like it's supposed.”Source discussion ↗
EphedrineMixed
“with 100mg caffeine, 200mg theanine, and 25mg ephedrine I still get pretty jittery. I've been taking 25 mg Ephedrine, 200 caffeine, 450 suntheanine, and 325 aspirin (not as a nootropic, to promote fat loss). Works pretty well for me.”Source discussion ↗
EphedrineMixed
“closest thing to adderall is ephedrine. I current switched from the ECA stack to the ECY stack (ephedrine, caffeine, Yohimbine) and it's working better for me.”Source discussion ↗
EphedrineMixed
“I suffer from insomnia and took 30mg ephedrine and in the morning and redosed mid day with no effect on sleep.”Source discussion ↗
EphedrineMixed
“ephedrine is the only thing i have found that works. marry that with caffeine withdrawal and i turn into a effin' monster.”Source discussion ↗
EphedrineMixed
“Something that worked great for me was Ephedrine through chewing Ephedra-Tea from China. I quit though because... made me kind of cold.”Source discussion ↗
EphedrineMixed
“Seriously, this wakes you up in the morning. Best workout I have had in a while. New bench press PB, and felt very focused.”Source discussion ↗
EphedrineMixed
“Both times it was effective in that my appetite was suppressed and I had plenty of energy. The weight-loss was regular, but I did feel jittery and unsettled at times.”Source discussion ↗
EphedrineMixed
“caffeine and ephedrine are really helping me out a ton...I started the ephedrine at the same time I got back into running after a long break, so it is hard to tell what is what.”Source discussion ↗
EphedrineMixed
“structurally ephedrine is an amphetamine and works with similar mechanisms as Adderall. My concern would be large spikes in blood pressure, which can be quite dangerous.”Source discussion ↗
EphedrineMixed
“I used it for over a year without stopping (stupidly). He is correct about the down-regulation but I never noticed any negative sides personally.”Source discussion ↗
EphedrineMixed
“Maybe, but I do have better workouts with caffeine, ephedrine and agmatine in my system.”Source discussion ↗
EphedrineMixed
“I see similar results from ephedrine and kratom, although I wouldn't say those are necessarily better alternatives than alcohol.”Source discussion ↗
EphedrineMixed
“Its big brother (ephedrine) makes me feel much nicer towards people "Social butterfly" talk to everybody kind of feel and way more positive”Source discussion ↗