What people actually say
5,470 first-hand quotes, shortened but never edited — each links to the original discussion.
AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
SAM-EMostly positive
“I also take SAM-e in the morning (200mg or 400mg per day depending on how I'm feeling) for my general depression/anxiety.”Source discussion ↗
SAM-EMostly positive
“I just started taking Sam-e and it’s helped with my ADHD and depression tremendously.”Source discussion ↗
SAM-EMostly positive
“Taking SAM-e completely changed my life from total lethargy with the only relief being Adderall or Ritalin to being a functional person, no side effects noticed and I only have to cycle it occasionally.”Source discussion ↗
SAM-EMostly positive
“SAMe and agmatine sulfate over the past year to be the two most noticeably helpful supplements i have ever taken for baseline energy/mood.”Source discussion ↗
SAM-EMostly positive
“Took me years to feel normal. Back then I used SAMe to help me.”Source discussion ↗
SAM-EMostly positive
“Low and behold it actually worked. Within five days I noticed a difference. The headaches are gone and I wake up everyday feeling refreshed.”Source discussion ↗
SAM-EMostly positive
“It helped mood and motivation, had more of a desire to get out and do things like be social. Felt like a weaker Wellbutrin to me.”Source discussion ↗
SAM-EMostly positive
“I was taking Sam-E for an energy boost when I go for a ride. I no longer take that stuff though because I've heard it disrupts sleep patterns.”Source discussion ↗
SAM-EMostly positive
“I had mild success with the supplement SAM-e. It definitely is stimulating—so should be taken in the AM—but no where near what any dedicated focus OTC peptide or supplement blends tend to do to me.”Source discussion ↗
SAM-EMostly positive
“sam-e - I'm not yet sure how this makes me feel better, because I take it since few days, but works wonders.”Source discussion ↗
SAM-EMostly positive
“I've had some success with SAM-e and Agmatine for anxiety, though these are not ssris.”Source discussion ↗
SAM-EMostly positive
“Another great stack I was into awhile back was SAMe+CDP choline+fasoracetam. That's definitely a 1-2 week stack but it worked *very* nicely for a high-productivity, focused edge.”Source discussion ↗
SAM-EMostly positive
“I felt more mental clarity and less brain fog after taking it for a month.”Source discussion ↗
SAM-EMostly positive
“SAM-e alone had no sleep shortening effect. At the end my natural sleep length increased to ~8.5h. At that point I resumed taking SAM-e.”Source discussion ↗
SAM-EMostly positive
“I have quit nicotine for a while now with help from what I believe is SAMe doing most of the heavy lifting with my mood... Starting at 200mg then working up to 400 Mg (I’m very happy with the results).”Source discussion ↗
SAM-EMostly positive
“I've seen some amazing improvement in such a short amount of time (even better than SSRI!). After a week, I decided to stop...started experiencing a horrible spike in OCD and anxiety.”Source discussion ↗
QuercetinMixed
“The above supplements have worked amazingly for my brain fog and motivation.”Source discussion ↗
QuercetinMixed
“The Thorne Quercetin has helped me a lot with seasonal allergies. I'd go as far as to say it had been more effective for me than either Claritin or Zyrtec.”Source discussion ↗
QuercetinMixed
“EGCG (green tea extact) and quercetin may two others to look into. Paired with NMN and 7,8DHF it seems to compound the energy improvements of NMN for me by a lot.”Source discussion ↗
QuercetinMixed
“Her kidney specialist said up to 500mg quercetin is fine per day, may actually be beneficial...I like NMN, I believe it's best paired with something like quercetin or another cd38 inhibitor for better absorption.”Source discussion ↗
QuercetinMixed
“Quercetin and bromelain, Vitamin K and D, astaxanthan, fish oil, turmeric, boron, msm, and coq10. I have osteoarthritis and this combo has been helping with the pain.”Source discussion ↗
QuercetinMixed
“Quercetin. I had it against Covid, but apparently it is also good for allergies. It worked.”Source discussion ↗
QuercetinMixed
“I feel like it does help against allergies and cold and flu season.”Source discussion ↗
QuercetinMixed
“I use it with quercetin because I heard it works in synergy”Source discussion ↗
QuercetinMixed
“I like quercetin but had to stop due to joint/tendon pain. I narrowed it down to that. It worked amazing for my mental clarity, energy and allergic rhinitis”Source discussion ↗
QuercetinMixed
“Quercetin has helped my daily allergy symptoms to the point that I no longer need Allegra”Source discussion ↗
QuercetinMixed
“I find quercetin works better for that. I take our quercetin phytosome every morning with the EGCG”Source discussion ↗
QuercetinMixed
“As well as up to 2g of Quercetin anhydrous from nootdep. For me the 1st was the closest feeling to amphetamines I've ever felt and up to 2g”Source discussion ↗
QuercetinMixed
“Quercetin gives me bad insomnia. Like, night owl energy. I still take it because I am a woman of science and I like to experiment, but the benefits are yet to be realized”Source discussion ↗
QuercetinMixed
“I sorta call quercetin 'the synergist' because it allows other plant compounds to have better bioavailability and pharmacokinetic profiles”Source discussion ↗
QuercetinMixed
“I get a crazy surge in goal oriented energy from Quercentin.”Source discussion ↗
QuercetinMixed
“quercetin makes me uncomfortably wired; definitely could fuel anxiety.”Source discussion ↗
FasoracetamMostly positive
“the tingle of disassociation and anxiety that lurks at the back of my mind at all times was gone, it felt as though i had finally been released from a prison cell.”Source discussion ↗
FasoracetamMostly positive
“I take faso + noopept right now and it is okay though nothing crazy, but there are many different options to try and explore there.”Source discussion ↗
FasoracetamMostly positive
“My memory recall, focus, energy and motivation are greatly improved while on fasoracetam.”Source discussion ↗
FasoracetamMostly positive
“Fasoracetam gives me a weak phenibut type stimulation/mood-boost throughout the whole day. Every day. With no crash.”Source discussion ↗
FasoracetamMostly positive
“For the first two weeks of use it gave me a rush in motivation and concentration, then an hour later the energy was replaced with a calming sensation with a continued positive effect on concentration.”Source discussion ↗
FasoracetamMostly positive
“Fasoracetam made a difference, but in terms of a clear night and day indistinguishable difference-- the most noticable for me has been Noopept.”Source discussion ↗
FasoracetamMostly positive
“Whenever im feeling really anxious i take fasoracetam ( like once a month )”Source discussion ↗
FasoracetamMostly positive
“As for Fascoracetam, I have at times found it useful in dealing with anxiety.”Source discussion ↗