Phosphatidylserine reviews: what real users say
We read 334 first-hand mentions of Phosphatidylserine from health and supplement communities. 110 of them say clearly how it went — and 73% of those say it helped.
Where people say it works: anxiety (95% of 39), sleep (86% of 37), focus (96% of 27), memory (91% of 22).
Most common complaints: drowsiness, fatigue, anhedonia, headache, hypotension. All side effects →
Positive experiences
“A supplement I have never seen on here that works great for me is Phosphatidylserine. Somehow awesome.”
“Phosphatidylserine (8/10): ... it made a pretty big impact as far as stress reduction for me. I felt less physical anxiety in social situations...”
“100 - 200mg Phosphatidylserine helps with my insomnia when I drink too much coffee during nightshift.”
“Phosphatidylserine has worked really well for anxiety. But careful with high doses, I got hypotension taking more than 400mg per day.”
“I've been trialing 300mg of phosphatidylserine 1 hour before bed for the cortisol lowering effect. Getting great sleep and it seems to also reduce my daytime anxiety by a lot.”
“When I took it out of their stacks, I noticed that they declined. Started again — they improved. It definitely works, but it's on the scale of weeks, not days.”
Negative and mixed experiences
“I have been taking this...and I have had great results...From my research, I found phosphatidylserine to be of little to no benefit on cognitive function.”
“Not feeling any difference.. I find it really weird I don't feel any different than I normally do.. no concentration boost or anything.”
“within 10-15 minutes if I'm feeling more down to Earth and relaxed...Over the last three weeks, I have seldom had these nervous thought loops.”
“Week 1 I was taking phosphatidylserine daily and I had 3 solid days (Wed to Sat) of calm, fear free, anxiety free living, but then I blunted cortisol too much and I couldn't stay awake.”
“I've been trying to calm it down with Phopshatidylserine, Vit C, and Magnesium, assuming it's something to do with Cortisol or Adrenaline. But I can't seem to get it to go away.”
“Took total of 300mg a day, split 3x. I got more horny than usual the first day I tried it and unfortunately after that I haven't felt any particular effect whatsoever.”
Quotes are verbatim and link to the original public discussion. Information only — not medical advice. How we collect reports