Conclusion: The effects of phosphatidylserine on overall symptoms of ADHD (ES 0.76; 95% CI: -0.07 to 1.60; p = 0.07) and hyperactivity-impulsivity (ES 0.24; 95% CI: -0.04 to 0.53; p = 0.09) were not statistically significant. Conclusions: Preliminary evidence suggests that phosphatidylserine may be effective for reducing symptoms of inattention in children with ADHD, although the quality of the evidence is low and additional research in this area is warranted.
Does Phosphatidylserine help with focus?
Yes, for most people. 96% of 27 people who reported on Phosphatidylserine for focus say it improved. 4% noticed no change and 0% say it got worse. That is above the typical result for focus (86% across 80 options).
Focus: what users report
96%better27 reports · medium confidence
26 better1 no change0 worse
Ranked #24 of 80 for focus.
What people say about Phosphatidylserine and focus
“A supplement I have never seen on here that works great for me is Phosphatidylserine. Somehow awesome.”
“I have been taking this...and I have had great results...From my research, I found phosphatidylserine to be of little to no benefit on cognitive function.”
“Not feeling any difference.. I find it really weird I don't feel any different than I normally do.. no concentration boost or anything.”
“within 10-15 minutes if I'm feeling more down to Earth and relaxed...Over the last three weeks, I have seldom had these nervous thought loops.”
What the research says
AResearch: Strong14 meta-analyses · 83 trials on PubMed
J Altern Complement Med · 2021
Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-AnalysisPLoS One · 2024
Safety and efficacy of antioxidant therapy in children and adolescents with attention deficit hyperactivity disorder: A systematic review and network meta-analysisConclusion: The rankings of safety and efficacy of the 12 antioxidants vary. Due to the low methodological quality of the included studies, the probability ranking cannot fully explain the clinical efficacy, and the results need to be interpreted with caution. More high-quality studies are still needed to verify our findings.
Side effects people mention
drowsiness 2fatigue 2anhedonia 1headache 1hypotension 1
What else is Phosphatidylserine used for?
Information only — not medical advice. How we count