Best for sleep

281 options people report for falling and staying asleep, sleep quality, ranked by the share of users who say it improved — weighted by how many reports there are.

Weight loss Appetite Focus Energy Sleep Anxiety Mood Memory Performance Recovery Pain & inflammation Digestion Libido Hormones Blood sugar Heart & lipids Skin & hair Immunity Longevity

Type:All Supplements Peptides Medications Substances Lifestyle Methods SARMs OtherResearch-backed only

30 results

155

TrazodoneMedication

Sleep Libido Mood

91% report better Sleep

22 reports

MixedAResearch: Strong

234

ProgesteroneMedication

Sleep

100% report better Sleep

10 reports

Mostly positiveAResearch: Strong

328

BenadrylMedication

Sleep Anxiety Focus

92% report better Sleep

12 reports

MixedBResearch: Moderate

431

GabapentinMedication

Anxiety Sleep Mood

90% report better Sleep

10 reports

MixedAResearch: Strong

525

HydroxyzineMedication

Sleep Anxiety

100% report better Sleep

7 reports

MixedAResearch: Strong

630

MirtazapineMedication

Sleep Mood Anxiety

100% report better Sleep

6 reports

MixedAResearch: Strong

770

TirzepatideMedication

Weight loss Appetite Mood

83% report better Sleep

6 reports

Mostly positiveAResearch: Strong

845

TestosteroneMedication

Performance Mood Libido

83% report better Sleep

6 reports

Mostly positiveAResearch: Strong

962

TadalafilMedication

Libido Performance Mood

100% report better Sleep

3 reports

Mostly positiveAResearch: Strong

1057

GuanfacineMedication

Focus Anxiety Sleep

100% report better Sleep

3 reports

Mostly positiveAResearch: Strong

1150

XanaxMedication

Anxiety Sleep Focus

100% report better Sleep

3 reports

MixedBResearch: Moderate

1239

HrtMedication

Energy Sleep

100% report better Sleep

3 reports

Mostly positiveAResearch: Strong

1319

AgomelatineMedication

Sleep Energy

100% report better Sleep

3 reports

Mostly positiveAResearch: Strong

1414

QuetiapineMedication

Sleep

100% report better Sleep

3 reports

Mostly negativeAResearch: Strong

1547

TRTMedication

Mood Energy Hormones

100% report better Sleep

2 reports

Mostly positiveAResearch: Strong

1635

IbuprofenMedication

Pain & inflammation Memory Focus

100% report better Sleep

2 reports

MixedAResearch: Strong

1734

BaclofenMedication

Anxiety Mood Sleep

100% report better Sleep

2 reports

Mostly positiveAResearch: Strong

1825

MetforminMedication

Performance Blood sugar Energy

100% report better Sleep

2 reports

MixedAResearch: Strong

1919

AntihistaminesMedication

Sleep Focus Anxiety

100% report better Sleep

2 reports

MixedAResearch: Strong

2021

DiphenhydramineMedication

Sleep

60% report better Sleep

5 reports

Mostly negativeAResearch: Strong

2146

ModafinilMedication

Focus Energy Mood

21% report better Sleep

39 reports

MixedAResearch: Strong

2232

MethylphenidateMedication

Focus Mood Anxiety

40% report better Sleep

5 reports

MixedAResearch: Strong

2365

SemaglutideMedication

Weight loss Appetite Energy

50% report better Sleep

2 reports

Mostly positiveAResearch: Strong

2414

DiazepamMedication

Anxiety Sleep

50% report better Sleep

2 reports

Mostly negativeAResearch: Strong

2549

PropranololMedication

Anxiety Sleep Focus

25% report better Sleep

4 reports

Mostly positiveAResearch: Strong

2638

BupropionMedication

Mood Energy Focus

25% report better Sleep

4 reports

MixedAResearch: Strong

2729

RitalinMedication

Focus Mood Anxiety

25% report better Sleep

4 reports

MixedAResearch: Strong

2836

VyvanseMedication

Focus Mood Energy

14% report better Sleep

7 reports

MixedBResearch: Moderate

2953

AdderallMedication

Focus Mood Energy

8% report better Sleep

12 reports

MixedAResearch: Strong

3025

Adderall XrMedication

Focus Mood Energy

0% report better Sleep

2 reports

MixedBResearch: Moderate

Minimum 2 reports per entry. Information only — not medical advice. How rankings work