PlainPill

Quercetin vs Vitamin D for immunity

Short answer: For immunity, users rate them about the same: 100% report improvement with Quercetin (10 reports) and 99% with Vitamin D (74 reports).

Quercetin has 207 meta-analyses and 232 randomized trials on PubMed; Vitamin D has 3,251 and 4,560.

Based on 239 reports about Quercetin and 2,323 about Vitamin D. Not medical advice.

Quercetin
Supplement
Vitamin D
Supplement
User score4548
Verdict
Mixed
Mostly positive
Positive
of reports that state an outcome
58%65%
Reports2392,323
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs207 / 2323,251 / 4,560
Mainly used for
Weight loss
% reporting improvement
—62% (8)
Appetite
% reporting improvement
—67% (3)
Focus
% reporting improvement
100% (6)82% (55)
Energy
% reporting improvement
100% (6)87% (215)
Sleep
% reporting improvement
60% (5)50% (105)
Anxiety
% reporting improvement
25% (4)65% (82)
Mood
% reporting improvement
100% (2)88% (308)
Memory
% reporting improvement
—83% (12)
Performance
% reporting improvement
—100% (23)
Recovery
% reporting improvement
—91% (11)
Pain & inflammation
% reporting improvement
64% (14)73% (30)
Digestion
% reporting improvement
—50% (14)
Libido
% reporting improvement
—80% (45)
Hormones
% reporting improvement
—87% (55)
Blood sugar
% reporting improvement
—100% (2)
Heart & lipids
% reporting improvement
—60% (15)
Skin & hair
% reporting improvement
67% (3)89% (28)
Immunity
% reporting improvement
100% (10)99% (74)
Longevity
% reporting improvement
100% (3)78% (9)
Common side effectsinsomnia, jitteriness, anxiety, overstimulationinsomnia, anxiety, fatigue, hypercalcemia
Typical dose reported500-1000 mgdaily
Quercetin
Latest review conclusion

The results of a meta-analysis of 12 RCTs indicate that TCM intervention can improve the clinical treatment efficacy of CAG. NPAs identified seven hub TCM and 13 target genes associated with their actions, while bioinformatics analysis identified two DEGs between normal and CAG gastric tissues. Finally, molecular docking was employed to reveal the mechanism of action of the active molecules in TCM on the DEGs. These findings not only reveal the mechanisms of action of the active components of the TCMs, but also provide support for the development of new drugs, ultimately blocking the progressi

Ann Med, 2023 ↗
What a user said
“The above supplements have worked amazingly for my brain fog and motivation.”
Full Quercetin profile →
Vitamin D
Latest review conclusion

These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.

Obes Rev, 2015 ↗
What a user said
“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
Full Vitamin D profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate