PlainPill

Quercetin vs Vitamin C for immunity

Short answer: For immunity, more users report improvement with Quercetin — 100% of 10 reports, versus 88% of 25 for Vitamin C.

Quercetin has 207 meta-analyses and 232 randomized trials on PubMed; Vitamin C has 738 and 2,072.

Based on 239 reports about Quercetin and 715 about Vitamin C. Not medical advice.

Quercetin
Supplement
Vitamin C
Supplement
User score4544
Verdict
Mixed
Mostly positive
Positive
of reports that state an outcome
58%68%
Reports239715
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs207 / 232738 / 2,072
Mainly used for
Weight loss
% reporting improvement
—100% (3)
Focus
% reporting improvement
100% (6)67% (9)
Energy
% reporting improvement
100% (6)100% (27)
Sleep
% reporting improvement
60% (5)71% (14)
Anxiety
% reporting improvement
25% (4)92% (13)
Mood
% reporting improvement
100% (2)86% (21)
Memory
% reporting improvement
—80% (5)
Performance
% reporting improvement
—25% (4)
Recovery
% reporting improvement
—100% (8)
Pain & inflammation
% reporting improvement
64% (14)79% (14)
Digestion
% reporting improvement
—75% (4)
Libido
% reporting improvement
—100% (2)
Hormones
% reporting improvement
—100% (4)
Heart & lipids
% reporting improvement
—75% (4)
Skin & hair
% reporting improvement
67% (3)96% (24)
Immunity
% reporting improvement
100% (10)88% (25)
Longevity
% reporting improvement
100% (3)100% (3)
Common side effectsinsomnia, jitteriness, anxiety, overstimulationstomach issues, kidney stones, insomnia, bone pain
Typical dose reported500-1000 mg2000 mg / daily
Quercetin
Latest review conclusion

The results of a meta-analysis of 12 RCTs indicate that TCM intervention can improve the clinical treatment efficacy of CAG. NPAs identified seven hub TCM and 13 target genes associated with their actions, while bioinformatics analysis identified two DEGs between normal and CAG gastric tissues. Finally, molecular docking was employed to reveal the mechanism of action of the active molecules in TCM on the DEGs. These findings not only reveal the mechanisms of action of the active components of the TCMs, but also provide support for the development of new drugs, ultimately blocking the progressi

Ann Med, 2023 ↗
What a user said
“The above supplements have worked amazingly for my brain fog and motivation.”
Full Quercetin profile →
Vitamin C
Latest review conclusion

The failure of vitamin C supplementation to reduce the incidence of colds in the general population indicates that routine vitamin C supplementation is not justified, yet vitamin C may be useful for people exposed to brief periods of severe physical exercise. Regular supplementation trials have shown that vitamin C reduces the duration of colds, but this was not replicated in the few therapeutic trials that have been carried out. Nevertheless, given the consistent effect of vitamin C on the duration and severity of colds in the regular supplementation studies, and the low cost and safety, it m

Cochrane Database Syst Rev, 2013 ↗
What a user said
“I know people say you get enough vitamin C from diet but I feel and look better when I supplement it.”
Full Vitamin C profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate