Nicotinamide vs Nicotine
Short answer: Overall, Nicotinamide gets more positive reports (100% vs 38%).
Nicotinamide has 120 meta-analyses and 239 randomized trials on PubMed; Nicotine has 1,323 and 3,241.
Based on 17 reports about Nicotinamide and 586 about Nicotine. Not medical advice.
| Nicotinamide Supplement | Nicotine Substance | |
|---|---|---|
| Users say it helped | 100%helped2 reports · few reports | 38%helped352 reports · high confidence |
| Verdict | Not enough data | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 120 / 239 | 1,323 / 3,241 |
| Mainly used for | ||
| Focus % reporting improvement | — | 92% (244) |
| Energy % reporting improvement | — | 94% (84) |
| Mood % reporting improvement | — | 65% (54) |
| Anxiety % reporting improvement | — | 55% (53) |
| Memory % reporting improvement | — | 79% (29) |
| Common side effects | None reported | addiction, anxiety, nausea, tolerance |
| Typical dose reported | — | 2 mg / cycled |
NADH supplementation is safe and has a low incidence of side effects. Future investigations are needed to evidence the clinical benefits regarding specific diseases and doses administered.
Am J Physiol Endocrinol Metab, 2024 ↗“I have a shitty demyelinating autoimmune bs going on and i feel so shit i feel all of them. Nicotinamide, nac. Selenium. B1!!! Everything.”
It provides crucial new knowledge about the efficacy of such interventions in preventing e-cigarette use and improving other outcomes (e.g., tobacco use, knowledge, intentions, attitudes, and mental health) among adolescents and the key characteristics associated with efficacious interventions. Our findings have important practical implications, highlighting future research directions for the development and evaluation of e-cigarette preventive interventions, along with the need to provide support to schools to help them identify and adopt evidence-based programs.
Prev Sci, 2024 ↗“Nicotine gum/pouches have been helpful for me especially when I am trying to focus at work.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate