Nicotine vs THC for mood
Short answer: For mood, users rate them about the same: 65% report improvement with Nicotine (54 reports) and 64% with THC (58 reports).
Nicotine has 1,323 meta-analyses and 3,241 randomized trials on PubMed; THC has 249 and 488.
Based on 586 reports about Nicotine and 434 about THC. Not medical advice.
| Nicotine Substance | THC Substance | |
|---|---|---|
| Users say it helped | 38%helped352 reports · high confidence | 26%helped295 reports · high confidence |
| Verdict | Mixed | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 1,323 / 3,241 | 249 / 488 |
| Mainly used for | ||
| Focus % reporting improvement | 92% (244) | 38% (40) |
| Anxiety % reporting improvement | 55% (53) | 33% (96) |
| Mood % reporting improvement | 65% (54) | 64% (58) |
| Sleep % reporting improvement | 11% (9) | 59% (95) |
| Energy % reporting improvement | 94% (84) | 56% (16) |
| Common side effects | addiction, anxiety, nausea, tolerance | anxiety, brain fog, vivid dreams, paranoia |
| Typical dose reported | 2 mg / cycled | 7 mg / once a week |
It provides crucial new knowledge about the efficacy of such interventions in preventing e-cigarette use and improving other outcomes (e.g., tobacco use, knowledge, intentions, attitudes, and mental health) among adolescents and the key characteristics associated with efficacious interventions. Our findings have important practical implications, highlighting future research directions for the development and evaluation of e-cigarette preventive interventions, along with the need to provide support to schools to help them identify and adopt evidence-based programs.
Prev Sci, 2024 ↗“Nicotine gum/pouches have been helpful for me especially when I am trying to focus at work.”
Cannabis use was also associated with increased relapse rates, more hospitalizations and pronounced positive symptoms in psychotic patients. We make recommendations about the type of research that is required to better characterize the relationship between cannabis use and the development and outcomes of psychosis.
Eur Arch Psychiatry Clin Neurosci, 2020 ↗“once a week I smoke a little weed before the gym (sativa Pre-roll sour diesel from medmen) and it actually made me feel normal.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate