Amphetamine vs Nicotine for focus
Short answer: For focus, more users report improvement with Nicotine — 92% of 244 reports, versus 85% of 428 for Amphetamine.
Amphetamine has 258 meta-analyses and 521 randomized trials on PubMed; Nicotine has 1,323 and 3,241.
Based on 878 reports about Amphetamine and 586 about Nicotine. Not medical advice.
| Amphetamine Medication | Nicotine Substance | |
|---|---|---|
| Users say it helped | 35%helped606 reports · high confidence | 38%helped352 reports · high confidence |
| Verdict | Mixed | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 258 / 521 | 1,323 / 3,241 |
| Mainly used for | ||
| Focus % reporting improvement | 85% (428) | 92% (244) |
| Energy % reporting improvement | 75% (146) | 94% (84) |
| Mood % reporting improvement | 48% (132) | 65% (54) |
| Anxiety % reporting improvement | 38% (56) | 55% (53) |
| Memory % reporting improvement | 50% (32) | 79% (29) |
| Common side effects | tolerance, anxiety, insomnia, jitteriness | addiction, anxiety, nausea, tolerance |
| Typical dose reported | Not listed | 2 mg / cycled |
Overall, despite a class effect of improving clinical response relative to placebo, there were few differences among the individual ADHD pharmacotherapies, and most studies were at risk of at least one important source of bias. Furthermore, the certainty of the evidence was very low to low for all outcomes, and there was limited reporting of long-term adverse events. As such, the choice between ADHD pharmacotherapies may depend on individual patient considerations, and future studies should assess the long-term effects of individual pharmacotherapies on patient-important outcomes, including qu
PLoS One, 2020 ↗“Unfortunately the only thing that's ever works for me was using adderall. I didn't feel hungry until 3 pm and it was perfect.”
It provides crucial new knowledge about the efficacy of such interventions in preventing e-cigarette use and improving other outcomes (e.g., tobacco use, knowledge, intentions, attitudes, and mental health) among adolescents and the key characteristics associated with efficacious interventions. Our findings have important practical implications, highlighting future research directions for the development and evaluation of e-cigarette preventive interventions, along with the need to provide support to schools to help them identify and adopt evidence-based programs.
Prev Sci, 2024 ↗“Nicotine gum/pouches have been helpful for me especially when I am trying to focus at work.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate