PlainPill

L-Tyrosine vs Modafinil for energy

Short answer: For energy, users rate them about the same: 89% report improvement with L-Tyrosine (119 reports) and 91% with Modafinil (301 reports).

L-Tyrosine has 10 meta-analyses and 38 randomized trials on PubMed; Modafinil has 155 and 297.

Based on 802 reports about L-Tyrosine and 1,097 about Modafinil. Not medical advice.

L-Tyrosine
Supplement
Modafinil
Medication
User score4745
Verdict
Mixed
Mixed
Positive
of reports that state an outcome
52%48%
Reports8021,097
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs10 / 38155 / 297
Mainly used for
Weight loss
% reporting improvement
—100% (5)
Appetite
% reporting improvement
—40% (15)
Focus
% reporting improvement
80% (163)84% (447)
Energy
% reporting improvement
89% (119)91% (301)
Sleep
% reporting improvement
33% (9)19% (75)
Anxiety
% reporting improvement
56% (34)26% (73)
Mood
% reporting improvement
82% (125)62% (88)
Memory
% reporting improvement
83% (6)71% (21)
Performance
% reporting improvement
100% (4)88% (17)
Pain & inflammation
% reporting improvement
67% (3)—
Libido
% reporting improvement
62% (8)25% (8)
Hormones
% reporting improvement
100% (4)—
Heart & lipids
% reporting improvement
—9% (11)
Skin & hair
% reporting improvement
60% (5)50% (2)
Common side effectsanxiety, insomnia, headache, jitterinessinsomnia, anxiety, headache, tolerance
Typical dose reported500 mg / dailyas needed
L-Tyrosine
Latest review conclusion

18F-FET static parameters alone showed a comparably high sensitivity in the differentiation between brain tumour true progression and TRC. Combining static and kinetic parameters provided improved diagnostic performance.

Nucl Med Commun, 2022 ↗
What a user said
“Tyrosine is just an excellent thing to add to any stack”
Full L-Tyrosine profile →
Modafinil
Latest review conclusion

Our findings represent the most comprehensive available evidence base to inform patients, families, clinicians, guideline developers, and policymakers on the choice of ADHD medications across age groups. Taking into account both efficacy and safety, evidence from this meta-analysis supports methylphenidate in children and adolescents, and amphetamines in adults, as preferred first-choice medications for the short-term treatment of ADHD. New research should be funded urgently to assess long-term effects of these drugs.

Lancet Psychiatry, 2018 ↗
What a user said
“It works well, but you will need to drink lots of water since its a diuretic... getting sucked into a single task is pretty common with me”
Full Modafinil profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate