PlainPill

L-Tyrosine

People mainly take L-Tyrosine for focus, mood, energy. Based on 802 first-hand reports and 10 meta-analyses & systematic reviews in the medical literature. Ranked #172 of 2,750 overall.

47
User score
Mixed
23% positive9% mixed12% negative56% unclear

Of reports that state an outcome, 52% are positive.

Clinical research
AStrong research base
10
meta-analyses
38
RCTs
5,271
papers

What L-Tyrosine does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

World Neurosurg · 2018 · Meta-analysis / systematic review
Accuracy of (18)F-FDOPA Positron Emission Tomography and (18)F-FET Positron Emission Tomography for Differentiating Radiation Necrosis from Brain Tumor Recurrence

Conclusion: Both 18F-FDOPA and 18F-FET exhibit moderate overall accuracy in diagnosing brain tumor recurrence from radiation necrosis. However, 18F-FDOPA is more adept at diagnosing glioma recurrence compared with brain metastases, and it is more effective than 18F-FET in diagnosing glioma recurrence.

PubMed 29625311 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

500 mgdaily
500mg-1g3-4x a week
500 mgbefore bed
1000 mgas reported
0.5-1 gpreworkout or mornings sometimes
750 mg x2daily

Reported side effects

How often each side effect came up across all reports.

anxiety ×10insomnia ×9headache ×7jitteriness ×5irritability ×5brain fog ×4drowsiness ×3depression ×3

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Tyrosine is just an excellent thing to add to any stack”
Source discussion ↗
“Have tried injecting BPC-157 subcutaneously and taking L-tyrosine but nothing has worked so far.”
Source discussion ↗
“I tried different forms and dosages of Magnesium, Zinc, L-Tyrosine, melatonin... most of them didn't provide any meaningful and noticeable benefits”
Source discussion ↗
“I'll throw down with this list of suggestions: L-tyrosine.”
Source discussion ↗
“found general happiness/stimulatory effects from: - Neurotransmitter precursors (L-tyrosine, 5-HTP)”
Source discussion ↗
Top discussions (5)

L-Tyrosine compared

Other options for focus

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate