Creatine vs L-Tyrosine for energy
Short answer: For energy, more users report improvement with Creatine — 97% of 205 reports, versus 89% of 119 for L-Tyrosine.
Creatine has 763 meta-analyses and 2,794 randomized trials on PubMed; L-Tyrosine has 10 and 38.
Based on 1,547 reports about Creatine and 802 about L-Tyrosine. Not medical advice.
| Creatine Supplement | L-Tyrosine Supplement | |
|---|---|---|
| User score | 52 | 47 |
| Verdict | Mostly positive | Mixed |
| Positive of reports that state an outcome | 69% | 52% |
| Reports | 1,547 | 802 |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 763 / 2,794 | 10 / 38 |
| Mainly used for | ||
| Weight loss % reporting improvement | 82% (11) | — |
| Appetite % reporting improvement | 67% (3) | — |
| Focus % reporting improvement | 92% (210) | 80% (163) |
| Energy % reporting improvement | 97% (205) | 89% (119) |
| Sleep % reporting improvement | 28% (71) | 33% (9) |
| Anxiety % reporting improvement | 68% (22) | 56% (34) |
| Mood % reporting improvement | 85% (103) | 82% (125) |
| Memory % reporting improvement | 91% (70) | 83% (6) |
| Performance % reporting improvement | 97% (316) | 100% (4) |
| Recovery % reporting improvement | 98% (62) | — |
| Pain & inflammation % reporting improvement | 50% (4) | 67% (3) |
| Digestion % reporting improvement | 0% (6) | — |
| Libido % reporting improvement | 82% (11) | 62% (8) |
| Hormones % reporting improvement | 75% (12) | 100% (4) |
| Blood sugar % reporting improvement | 100% (3) | — |
| Heart & lipids % reporting improvement | 67% (6) | — |
| Skin & hair % reporting improvement | 17% (12) | 60% (5) |
| Longevity % reporting improvement | 100% (4) | — |
| Common side effects | hair loss, stomach issues, insomnia, water retention | anxiety, insomnia, headache, jitteriness |
| Typical dose reported | daily | 500 mg / daily |
The results of the meta-analysis suggest that creatine supplementation did not significantly alter serum creatinine levels (standardized mean difference = 0.48, 95% confidence interval 0.24-0.73, P = .001, I2 = 22%), and did not alter plasma urea values (standardized mean difference = 1.10, 95% confidence interval 0.34-1.85, P = .004, I2 = 28%). The findings indicate that creatine supplementation does not induce renal damage in the studied amounts and durations.
J Ren Nutr, 2019 ↗“Creatine - mental and physical performance enhancement”
18F-FET static parameters alone showed a comparably high sensitivity in the differentiation between brain tumour true progression and TRC. Combining static and kinetic parameters provided improved diagnostic performance.
Nucl Med Commun, 2022 ↗“Tyrosine is just an excellent thing to add to any stack”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate